Epidemiologic studies detected an inverse relationship between HDL (high-density
lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease …

Citrate plays a central role in cancer cells' metabolism and regulation. Derived from
mitochondrial synthesis and/or carboxylation of α-ketoglutarate, it is cleaved by ATP-citrate …

The differentiation and effector functions of both the innate and adaptive immune system are
inextricably linked to cellular metabolism. The features of metabolism which affect both arms …

FOXP3+ Tregs rely on fatty acid β-oxidation–driven (FAO-driven) oxidative phosphorylation
(OXPHOS) for differentiation and function. Recent data demonstrate a role for Tregs in the …

Summary The cytokine interleukin-23 (IL-23) is involved in the pathogenesis of inflammatory
and autoimmune conditions including inflammatory bowel disease (IBD). IL23R is enriched …

Lipoproteins in cerebrospinal fluid (CSF) of the central nervous system (CNS) resemble
plasma high-density lipoproteins (HDLs), which are a compositionally and structurally …

Coronary artery disease, the leading cause of death in the developed and developing
countries, is prevalent in diabetes mellitus with 68% cardiovascular disease (CVD)-related …

High-density lipoprotein (HDL) plays an important role in lipid metabolism and especially
contributes to the reverse cholesterol transport pathway. Over recent years it has become …

Mesenchymal stem cell (MSC) based therapies are currently being evaluated as a putative
therapeutic in numerous human clinical trials. Recent reports have established that …

Lipoproteins interact with immune cells, macrophages and endothelial cells-key players of
the innate and adaptive immune system. High-density lipoprotein (HDL) particles seem to …