The direct binding of Plasmodium vivax AMA1 to erythrocytes defines a RON2-independent invasion pathway

SK Lee, LM Low, JF Andersen… - Proceedings of the …, 2023 - National Acad Sciences
We used a transgenic parasite in which Plasmodium falciparum parasites were genetically
modified to express Plasmodium vivax apical membrane antigen 1 (PvAMA1) protein in …

Activation of TCR Vδ1+ and Vδ1− Vδ2− γδ T cells upon controlled infection with Plasmodium falciparum in Tanzanian volunteers

T Rutishauser, M Lepore, D Di Blasi… - The Journal of …, 2020 - journals.aai.org
Our understanding of the human immune response to malaria remains incomplete. Clinical
trials using whole-sporozoite-based vaccination approaches such as the Sanaria PfSPZ …

Optical tweezers to measure the elasticity of red blood cells: A tool to study the erythrocyte response to antimalarials

D Dorta, P Padmore, R Correa, L Pineda… - Frontiers in …, 2024 - frontiersin.org
The Plasmodium falciparum parasite infected more than 240 million people and killed
around 600,000 patients last year alone. A key aspect of the pathophysiology of P …

Evidence against a role of elevated intracellular Ca2+ during Plasmodium falciparum preinvasion

V Introini, A Crick, T Tiffert, J Kotar, YC Lin, P Cicuta… - Biophysical …, 2018 - cell.com
Severe malaria is primarily caused by Plasmodium falciparum parasites during their asexual
reproduction cycle within red blood cells. One of the least understood stages in this cycle is …

Mechanical Characterization of the Erythrocyte Membrane Using a Capacitor-Based Technique

D Dorta, C Plazaola, J Carrasco, MF Alves-Rosa… - Micromachines, 2024 - mdpi.com
Pathological processes often change the mechanical properties of cells. Increased rigidity
could be a marker of cellular malfunction. Erythrocytes are a type of cell that deforms to …

Continuous-flow separation of malaria-infected human erythrocytes using DC dielectrophoresis: an electrokinetic modeling and simulation

M Nahavandi - Industrial & Engineering Chemistry Research, 2016 - ACS Publications
This paper presents a particle tracing numerical approach into direct current insulating
dielectrophoretic (DC-iDEP) cell sorting using an innovative microfluidic device capable of …

Identifying Merozoite Targets of Protective Immunity Against Plasmodium falciparum Malaria

G Kamuyu - 2017 - oro.open.ac.uk
The observation that individuals living in malaria endemic regions who are repeatedly
infected with P. falciparum can acquire immunity, first to severe, then to uncomplicated …

A mathematical model of ion homeostasis in the malaria parasite, Plasmodium falciparum

J Diemer - 2023 - edoc.hu-berlin.de
Malaria is currently responsible for more than 200 million estimated cases and half a million
deaths annually, with the majority of cases and deaths attributable to Plasmodium …

Efecto de la rigidez eritrocitaria como biomarcador en la invasión de Plasmodium falciparum

ED Alaín Borbón - 2024 - up-rid.up.ac.pa
La malaria es una enfermedad transmitida por parásitos del género Plasmodium que se
trasmite por la picadura de mosquitos hembras del género Anopheles que inoculan el …

Evaluation of a mutation on 26s proteasome subunit of plasmodium falciparum towards antimalarial resistance

AF Gonçalves - 2021 - search.proquest.com
Malária continua a ser uma das principais causas de morte em todo o mundo,
especialmente nas regiões tropicais. Esta é causada por parasitas protozoários do género …