Host response mechanisms in periodontal diseases

N Silva, L Abusleme, D Bravo, N Dutzan… - Journal of Applied Oral …, 2015 - SciELO Brasil
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis
and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm …

A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes

JJ Taylor, PM Preshaw, E Lalla - Journal of clinical …, 2013 - Wiley Online Library
Aims To review the evidence for the molecular and cellular processes that may potentially
link periodontal disease and diabetes. The pathogenic roles of cytokines and metabolic …

Diabetes as a risk factor for periodontal disease—plausible mechanisms

D Polak, T Sanui, F Nishimura… - Periodontology 2000, 2020 - Wiley Online Library
The present narrative review examines the scientific evidence of the biological mechanisms
that may link periodontitis and diabetes, as a source of comorbidity. Publications regarding …

[HTML][HTML] Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

S Bhattacharyya, K Kelley, DS Melichian… - The American journal of …, 2013 - Elsevier
Because recent studies implicate Toll-like receptors (TLRs) in the pathogenesis of fibrosis,
we sought to investigate the in vitro and in vivo role and mechanism of TLR4-mediated …

High glucose concentrations alter the biomineralization process in human osteoblastic cells

A García-Hernández, H Arzate, I Gil-Chavarría, R Rojo… - Bone, 2012 - Elsevier
Diabetes mellitus (DM) may alter bone remodeling, as osteopenia and osteoporosis are
among the complications. Moreover, DM increases the risk and severity of chronic …

Chemokine function in periodontal disease and oral cavity cancer

SE Sahingur, WA Yeudall - Frontiers in immunology, 2015 - frontiersin.org
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a
wide range of activities that include recruitment of immune cells to sites of infection and …

The role of Toll‐like receptors in periodontitis

B Song, YL Zhang, LJ Chen, T Zhou, WK Huang… - Oral …, 2017 - Wiley Online Library
Periodontitis is a common infectious disease. Recent studies have indicated that the
progression of periodontitis may be regulated by interactions between host immunity and …

Lipopolysaccharide differentially affects the osteogenic differentiation of periodontal ligament stem cells and bone marrow mesenchymal stem cells through Toll-like …

C Li, B Li, Z Dong, L Gao, X He, L Liao, C Hu… - Stem cell research & …, 2014 - Springer
Introduction Periodontitis is initiated and sustained by bacteria. However, the mechanism of
bacteria induced periodontitis is still unknown. We hypothesized that bacterial components …

Periodontitis: oral complication of diabetes

PM Preshaw, SM Bissett - Endocrinology and Metabolism …, 2013 - endo.theclinics.com
Periodontitis is a common chronic inflammatory disease that affects the tissues that support
and invest the teeth. These tissues include the gingiva (or gum, the visible part of pink tissue …

State of evidence on oral health problems in diabetic patients: a critical review of the literature

MÁ González-Moles, P Ramos-García - Journal of Clinical Medicine, 2021 - mdpi.com
Diabetes mellitus (DM) is a global health problem, having recognized that in the next 20
years the number of diabetic patients in the world will increase to 642 million. DM exerts …