Canine parvovirus and its non-structural gene 1 as oncolytic agents: mechanism of action and induction of anti-tumor immune response

R Arora, WA Malla, A Tyagi, S Mahajan… - Frontiers in …, 2021 - frontiersin.org
The exploration into the strategies for the prevention and treatment of cancer is far from
complete. Apart from humans, cancer has gained considerable importance in animals …

[HTML][HTML] Newcastle disease virus infection triggers HMGB1 release to promote the inflammatory response

Y Qu, Y Zhan, S Yang, S Ren, X Qiu, ZU Rehamn… - Virology, 2018 - Elsevier
High mobility group box 1 (HMGB1) is a key member of the “danger associated molecular
patterns”(DAMPs) which plays important roles in systemic inflammation and has a …

Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I

L Li, JJ Wu, F Zheng, Q Tang, WY Wu… - Journal of Experimental & …, 2016 - Springer
Abstract Background Polyphyllin I (PPI), a bioactive phytochemical extracted from the
Rhizoma of Paris polyphylla, has been reported to exhibit anti-cancer activity. However, the …

Newcastle disease virus V protein inhibits apoptosis in DF-1 cells by downregulating TXNL1

C Wang, Z Chu, W Liu, Y Pang, X Gao, Q Tang, J Ma… - Veterinary …, 2018 - Springer
Many viral proteins are related to suppressing apoptosis in target cells and are hence
beneficial to viral replication. The V protein of Newcastle disease virus (NDV) is one such …

Death-inducer obliterator 1 (DIDO1) silencing suppresses the growth of bladder cancer cells through decreasing SAPK/JNK signaling cascades.

J Li, AS Wang, S Wang, CY Wang, S Xue, WY Li… - …, 2020 - search.ebscohost.com
Death inducer obliterator (DIDO) is involved in apoptosis and embryonic stem cell self-
renewal. Here, we investigate the effect of DIDO1 on bladder cancer cells and clarify the …

Transcriptome profiling of Canine Parvovirus 2 Nonstructural gene 1 (CPV2. NS1) transfected 4T1 mice mammary tumor cells to elucidate its oncolytic effects

R Arora, WA Malla, A Tyagi, S Saxena… - International Journal of …, 2024 - Elsevier
Oncolytic viral gene therapy is a directed approach to target cancer cells without affecting
healthy cells of the body. Canine parvovirus (CPV2) is an oncolytic virus that precisely …

HN protein of Newcastle disease virus sensitizes HeLa cells to TNF-α-induced apoptosis by downregulating NF-κB expression

RS Rajmani, SK Gupta, PK Singh, RK Gandham… - Archives of …, 2016 - Springer
Hemagglutinin neuraminidase (HN) is a membrane protein of Newcastle disease virus
(NDV) with the ability to induce apoptosis in many transformed cell lines. TNF-α is a multi …

Bta-miR-98 suppresses replication of caprine parainfluenza virus type 3 through inhibiting apoptosis by targeting caspase-3

J Li, C Zhong, Z Liao, L Mao, W Li, M Sun… - Frontiers in …, 2020 - frontiersin.org
Caprine parainfluenza virus type 3 (CPIV3) is an emerging respiratory pathogen that affects
the sheep and goat industry in China and possibly other countries around the world …

Identification of long noncoding RNAs of silkworm at the early stage of Bombyx mori bidensovirus infection

Y Chen, Z Wang, C Wu, H Li, H Qian… - Archives of Insect …, 2024 - Wiley Online Library
Bombyx mori bidensovirus (BmBDV) is one of the most important pathogens of silkworm. It
mainly infects midgut cells of silkworm and causes losses to the sericulture industry. Long …

[HTML][HTML] The TRK-fused gene negatively regulates interferon signaling by inhibiting TBK1 phosphorylation during PPMV-1 infection

Y Tian, R Xue, C Yu, L Liu, S Chen, J Lv - Acta Virologica, 2023 - frontierspartnerships.org
TRK-fused gene (TFG, tropomyosin-receptor kinase fused gene) is known to negatively
regulate the retinoic acid inducible gene (RIG)-I-like receptor (RLR)-mediated interferon …