Redox equilibria and the modulation of redox signalling play crucial roles in physiological
processes. Overproduction of reactive oxygen species (ROS) disrupts the body's antioxidant …

A wide spectrum of comorbidities has been associated with Parkinson's disease (PD), a
progressive neurodegenerative disease that affects more than seven million people …

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In the early sixties, a discussion started regarding the association between Parkinson's
disease (PD) and type II diabetes mellitus (T2DM). Today, this potential relationship is still a …

Environmental and genetic factors are likely to be involved in the pathogenesis of
Parkinson's disease (PD), the second most prevalent neurodegenerative disease among the …

Two series of dimethoxy-halogenated chalcones (DM1–DM20) were synthesized and tested
for their ability to inhibit monoamine oxidase (MAOs). Compound DM2 exhibited the most …

Neurodegenerative diseases are rarely caused by a mutation in a single gene but rather
influenced by a combination of genetic, epigenetic and environmental factors. Emerging …

General medical problems and complications have a major impact on the quality of life in all
stages of Parkinson's disease. To introduce an effective treatment, a comprehensive …

Network biology has become a powerful tool to dissect the molecular mechanisms triggering
neurodegeneration. Recent developments in network biology have led to the discovery of …

Objectives Ischemic cerebral infarction (ICI) is a fatal neurovascular disorder. A
bioinformatics approach based on single-cell and bulk RNA-seq analyses was applied to …