[HTML][HTML] Multi-component Chinese medicine formulas for drug discovery: state of the art and future perspectives

C Zhang, G Chen, G Tang, X Xu, Z Feng, Y Lu… - Acta Materia …, 2023 - scienceopen.com
For hundreds of years, the drug discovery and development industry has aimed at
identifying single components with a clear mechanism of action as desirable candidates for …

[HTML][HTML] A Chinese classical prescription Guizhi-Fuling Wan in treatment of ovarian cancer: an overview

XZ Wang, PW Su, Q Hao, XY Zhang, L Xia… - Biomedicine & …, 2022 - Elsevier
Ovarian cancer is one of the three most common female reproductive system cancers and
has been a hot topic in the field of gynecology and oncology. Currently, surgery with …

[HTML][HTML] Poria cocos polysaccharide prevents alcohol-induced hepatic injury and inflammation by repressing oxidative stress and gut leakiness

Y Jiang, L Wang, W Chen, Y Duan, M Sun… - Frontiers in …, 2022 - frontiersin.org
Alcoholic liver disease (ALD) is a major worldwide chronic liver disease accompanied by
hepatic inflammation, gut leakiness, and abnormal oxidative stress. Our previous study …

[HTML][HTML] The potential mechanism of Guizhi Fuling Wan effect in the treatment of cervical squamous cell carcinoma: a bioinformatics analysis investigation

X Wang, T Wang, X Jiang, Y Ruan, J Wang, C Qi - Medicine, 2024 - journals.lww.com
As a global malignancy with high mortality rate, targeted drug development for Uterine
Cervical Neoplasms is an important direction. The traditional formula Guizhi Fuling Wan …

[HTML][HTML] Complementary authentication of Chinese herbal products to treat endometriosis using DNA metabarcoding and HPTLC shows a high level of variability

F Mück, F Scotti, Q Mauvisseau… - Frontiers in …, 2023 - frontiersin.org
Traditional Chinese Medicine (TCM) is popular for the treatment of endometriosis, a complex
gynecological disease that affects 10% of women globally. The growing market for TCMs …

Metabolomic profiling and comparison of major cinnamon species using UHPLC–HRMS

Y Wang, PB Harrington, P Chen - Analytical and bioanalytical chemistry, 2020 - Springer
The metabolomic profiles of four major species of cinnamon (Cinnamomum verum, C.
burmannii, C. loureiroi, and C. cassia) were investigated by ultra-high-performance liquid …

Protective mechanism of traditional Chinese medicine guizhi fuling pills against carbon tetrachloride-induced kidney damage is through inhibiting oxidative stress …

B Xu, J Zheng, X Tian, F Yuan, Y Zhou, Z Yang, X Ding - Phytomedicine, 2022 - Elsevier
Background Chemical or drug-induced kidney damage has been recognized as a critical
cause of kidney failure. The oxidative stress, inflammation, and imbalance of intestinal flora …

[HTML][HTML] Antihepatofibrotic effect of Guizhifuling pill (桂枝茯苓丸) on carbon tetrachloride-induced liver fibrosis in mice

XU Baogui, J Zheng, T Xiaoxiao, Y Falei… - Journal of Traditional …, 2022 - ncbi.nlm.nih.gov
OBJECTIVE: To evaluate the protective effects and the underlying mechanism of
Guizhifuling pill (桂枝茯苓丸, GZFL) on carbon tetrachloride (CCl 4)-induced hepatic fibrosis …

The multiple pharmacologic functions and mechanisms of action of guizhi fuling formulation

J Gao, J Yang, Z Lu, X Dong… - … Based Complementary and …, 2022 - Wiley Online Library
Objectives. Guizhi Fuling Formulation (GZFL), a traditional Chinese medical formulation,
consists of Cinnamomi Ramulus, Paeoniae Radix Alba (or Paeoniae Radix Rubra), Moutan …

[HTML][HTML] Gallic acid ameliorates endometrial hyperplasia through the inhibition of the PI3K/AKT pathway and the down-regulation of cyclin D1 expression

C Zheng, Y Wang, B Bi, W Zhou, X Cao… - Journal of …, 2024 - Elsevier
Background Gallic acid (GA) is an organic compound with phenolic properties that occurs
naturally and can be found in Guizhi Fuling capsules, showcasing a wide range of biological …