Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

NDM metallo-β-lactamases and their bacterial producers in health care settings

W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - Am Soc Microbiol
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Recovery of gut microbiota of healthy adults following antibiotic exposure

A Palleja, KH Mikkelsen, SK Forslund, A Kashani… - Nature …, 2018 - nature.com
To minimize the impact of antibiotics, gut microorganisms harbour and exchange antibiotics
resistance genes, collectively called their resistome. Using shotgun sequencing-based …

Forecasting the dissemination of antibiotic resistance genes across bacterial genomes

MMH Ellabaan, C Munck, A Porse, L Imamovic… - Nature …, 2021 - nature.com
Antibiotic resistance spreads among bacteria through horizontal transfer of antibiotic
resistance genes (ARGs). Here, we set out to determine predictive features of ARG transfer …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

Y Zou, W Xue, G Luo, Z Deng, P Qin, R Guo… - Nature …, 2019 - nature.com
Reference genomes are essential for metagenomic analyses and functional characterization
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …

Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

Bacteria antibiotic resistance: New challenges and opportunities for implant‐associated orthopedic infections

B Li, TJ Webster - Journal of Orthopaedic Research®, 2018 - Wiley Online Library
There has been a dramatic increase in the emergence of antibiotic‐resistant bacterial
strains, which has made antibiotic choices for infection control increasingly limited and more …

Antibiotic-resistance genes in waste water

A Karkman, TT Do, F Walsh, MPJ Virta - Trends in microbiology, 2018 - cell.com
Waste water and waste water treatment plants can act as reservoirs and environmental
suppliers of antibiotic resistance. They have also been proposed to be hotspots for …

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

B Jia, AR Raphenya, B Alcock… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.
mcmaster. ca) is a manually curated resource containing high quality reference data on the …