[HTML][HTML] Drug resistance in liver flukes

I Fairweather, GP Brennan, REB Hanna… - International Journal for …, 2020 - Elsevier
Liver flukes include Fasciola hepatica, Fasciola gigantica, Clonorchis sinensis, Opisthorchis
spp., Fascioloides magna, Gigantocotyle explanatum and Dicrocoelium spp. The two main …

Host pharmacokinetics and drug accumulation of anthelmintics within target helminth parasites of ruminants

A Lifschitz, C Lanusse, L Alvarez - New Zealand Veterinary …, 2017 - Taylor & Francis
Anthelmintic drugs require effective concentrations to be attained at the site of parasite
location for a certain period to assure their efficacy. The processes of absorption …

Oxfendazole: a promising agent for the treatment and control of helminth infections in humans

AE Gonzalez, EE Codd, J Horton… - Expert review of anti …, 2019 - Taylor & Francis
ABSTRACT Introduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl]
carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite …

Bovine fasciolosis: control strategies based on the location of Galba truncatula habitats on farms

G Knubben-Schweizer, PR Torgerson - Veterinary parasitology, 2015 - Elsevier
Infection of livestock with Fasciola hepatica is a worldwide, economically important and
increasing problem. Even though, bovine fasciolosis can be a disease associated with …

Triclabendazole for the treatment of human fascioliasis and the threat of treatment failures

L Marcos, V Maco, A Terashima - Expert Review of Anti-infective …, 2021 - Taylor & Francis
Introduction The only drug effective against the infection caused by Fasciola hepatica or F.
gigantica is triclabendazole (TCBZ), recommended by the WHO and recently approved by …

[PDF][PDF] Comparative efficacy of six anthelmintic treatments against natural infection of Fasciola species in sheep.

MN Khan, MS Sajid, HM Rizwan, AQ Abdul Qudoos… - 2017 - researchgate.net
Parasitism is one of the important issues all over the globe and reducing the productivity of
animals (Vercruysse and Claerebout, 2001; Solcan et al., 2015; Asif et al., 2016). The …

New developments in epidemiology, diagnosis, and treatment of fascioliasis

MM Cabada, AC White Jr - Current opinion in infectious diseases, 2012 - journals.lww.com
New developments in epidemiology, diagnosis, and treatment o... : Current Opinion in Infectious
Diseases New developments in epidemiology, diagnosis, and treatment of fascioliasis : Current …

Solving the delivery problems of triclabendazole using cyclodextrins

D Real, D Leonardi, RO Williams, MA Repka… - Aaps Pharmscitech, 2018 - Springer
Triclabendazole is the first-line drug of choice to treat and control fasciolasis, a neglected
parasitic human disease. It is a class II/IV compound according to the Biopharmaceutics …

[HTML][HTML] Anthelmintic effects of some medicinal plants on different life stages of Fasciola hepatica: Evidence on oxidative stress biomarkers, and DNA damage

M Allahyari, F Malekifard… - PLOS Neglected Tropical …, 2024 - journals.plos.org
Fasciolosis caused by Fasciola hepatica is a major public health and economic problem
worldwide. Due to the lack of a successful vaccine and emerging resistance to the drug …

[HTML][HTML] New benzimidazole derivative compounds with in vitro fasciolicidal properties

E Valderas-García, V Castilla-Gómez de Agüero… - Parasites & …, 2024 - Springer
Background Control of the zoonotic food-borne parasite Fasciola hepatica remains a major
challenge in humans and livestock. It is estimated that annual economic losses due to …