Tissues within the central nervous system (CNS) have generally been regarded as
immunologically privileged. However, in recent decades, it has been shown that immune …

Background Emerging evidence indicates that reactive microglia-initiated inflammatory
responses are responsible for secondary damage after primary traumatic spinal cord injury …

Substantial scientific progress has been made in the past 50 years in delineating many of
the biological mechanisms involved in the primary and secondary injuries following trauma …

Spinal cord injury (SCI) repair remains a major challenge in regenerative medicine. While
biomaterials have shown promise in tissue engineering, they often lack the directional cues …

Understanding the link between mother's obesity and regulation of the child's appetite is a
prerequisite for the design of successful preventive strategies. Beyond the possible …

The purpose of this study was to examine neuronal activity levels in the hindlimb area of
motor cortex following spinal cord injury (SCI) in rats and compare the results with …

Open-field behavioral scoring is widely used to assess spinal cord injury (SCI) outcomes,
but has limited usefulness in describing subtle changes important for posture and …

Genomic screened homeobox 1 (Gsx1 or Gsh1) is a neurogenic transcription factor required
for the generation of excitatory and inhibitory interneurons during spinal cord development …

Spinal cord injury (SCI) is one of the most devastating injuries for patients. Glial cell line–
derived neurotrophic factor (GDNF) is an important neurotrophic factor for the regeneration …

Emerging evidence indicates that microglia activation plays an important role in spinal cord
injury (SCI) caused by trauma. Studies have found that inhibiting the Rho/Rho-associated …