The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …

Ribosomal RNAs are the most abundant and universal noncoding RNAs in living organisms.
In eukaryotes, three of the four ribosomal RNAs forming the 40S and 60S subunits are borne …

The essential cellular process of ribosome biogenesis is at the nexus of various signalling
pathways that coordinate protein synthesis with cellular growth and proliferation. The fact …

Abstract Box C/D and H/ACA RNPs are essential ribonucleoprotein particles that are found
throughout both eukaryotes [small nucleolar RNPs (snoRNPs)] and archaea [snoRNP‐like …

Ribosomes play a pivotal role in the molecular life of every cell. Moreover, synthesis of
ribosomes is one of the most energetically demanding of all cellular processes. In eukaryotic …

Ribosome biogenesis is a fundamental process that provides cells with the molecular
factories for cellular protein production. Accordingly, its misregulation lies at the heart of …

The biogenesis of eukaryotic ribosomes is a complicated process during which the
transcription, modification, folding, and processing of the rRNA is coupled with the ordered …

The exosome regulates the processing, degradation, and surveillance of a plethora of RNA
species. However, little is known about how the exosome recognizes and is recruited to its …

Superfamily 2 helicase proteins are ubiquitous in RNA biology and have an extraordinarily
broad set of functional roles. Central among these roles are the promotion of …

Assembly factors (AFs) prevent premature translation initiation on small (40S) ribosomal
subunit assembly intermediates by blocking ligand binding. However, it is unclear how AFs …