Towards next-generation diagnostic pathology: AI-empowered label-free multiphoton microscopy

S Wang, J Pan, X Zhang, Y Li, W Liu, R Lin… - Light: Science & …, 2024 - nature.com
Diagnostic pathology, historically dependent on visual scrutiny by experts, is essential for
disease detection. Advances in digital pathology and developments in computer vision …

Methods for bladder cancer diagnosis–The role of autofluorescence and photodynamic diagnosis

K Bochenek, D Aebisher, A Międzybrodzka… - Photodiagnosis and …, 2019 - Elsevier
Bladder cancer is one of the most common Genito-urinary malignant tumors in humans.
Improved diagnostic and therapeutic methods that aim to reduce rates of recurrence and …

High-speed label-free ultraviolet photoacoustic microscopy for histology-like imaging of unprocessed biological tissues

X Li, L Kang, Y Zhang, TTW Wong - Optics letters, 2020 - opg.optica.org
Ultraviolet photoacoustic microscopy (UV-PAM) has recently been demonstrated as a
potential imaging tool for surgical margin analysis (SMA). UV-PAM does not require staining …

Advanced optical imaging techniques for bladder cancer detection and diagnosis: a systematic review

MJ Remmelink, Y Rip, JA Nieuwenhuijzen… - BJU …, 2024 - Wiley Online Library
Objectives To systematically assess the current available literature concerning advanced
optical imaging methods for the detection and diagnosis of bladder cancer (BCa), focusing …

Non-muscle-invasive bladder cancer: a vision for the future

PU Malmström, S Agrawal, M Bläckberg… - … journal of urology, 2017 - Taylor & Francis
The management of non-muscle-invasive bladder cancer (NMIBC) has evolved from the first
reports on bladder endoscopy and transurethral resection to the introduction of adjuvant …

Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions

T Matsui, H Mizuno, T Sudo, J Kikuta, N Haraguchi… - Scientific reports, 2017 - nature.com
Multiphoton excitation microscopy (MPM) is regarded as an effective tool that enables the
visualization of deep regions within living tissues and organs, with little damage. Here, we …

Ex vivo confocal fluorescence microscopy for rapid evaluation of tissues in surgical pathology practice

S Krishnamurthy, A Cortes, M Lopez… - … of Pathology & …, 2018 - meridian.allenpress.com
Context.—Optical imaging techniques are currently available for imaging tissues without the
need for any type of extensive tissue preparation. There are several applications for their …

Implementation of fluorescence confocal mosaicking microscopy by “early adopter” Mohs surgeons and dermatologists: recent progress

M Jain, M Rajadhyaksha… - Journal of Biomedical …, 2017 - spiedigitallibrary.org
Confocal mosaicking microscopy (CMM) enables rapid imaging of large areas of fresh tissue
ex vivo without the processing that is necessary for conventional histology. When performed …

In vivo and ex vivo microscopy: moving toward the integration of optical imaging technologies into pathology practice

WA Wells, M Thrall, A Sorokina… - … of pathology & …, 2019 - meridian.allenpress.com
The traditional surgical pathology assessment requires tissue to be removed from the
patient, then processed, sectioned, stained, and interpreted by a pathologist using a light …

Multiphoton microscopy in surgical oncology-a systematic review and guide for clinical translatability

TT König, J Goedeke, OJ Muensterer - Surgical Oncology, 2019 - Elsevier
Background Multiphoton microscopy (MPM) facilitates three-dimensional, high-resolution
functional imaging of unlabeled tissues in vivo and ex vivo. This systematic review discusses …