Current clinical treatment strategies for the bypassing of small diameter (< 6 mm) blood
vessels in the management of cardiovascular disease frequently fail due to a lack of suitable …

Pro-angiogenic bone marrow (BM) cells include subsets of hematopoietic cells that provide
vascular support and endothelial progenitor cells (EPCs), which under certain permissive …

Autologous or synthetic vascular grafts are used routinely for providing access in
hemodialysis or for arterial bypass in patients with cardiovascular disease. However, some …

Blood vessels form an important interface between the environment and the organism by
carrying oxygen and nutrients to all cells and thus determining cellular metabolism. It is …

Accumulating evidence indicates the impact of endothelial progenitor cells (EPCs) in
vascular repair. In patients, the number of EPCs is negatively correlated with the severity of …

Cell membrane coating has recently emerged as a promising biomimetic approach to
engineering nanoparticles (NPs) for targeted drug delivery. However, simple cell membrane …

Integrin-associated signalling renders cells more resistant to genotoxic anti-cancer agents
like ionizing radiation and chemotherapeutic substances, a phenomenon termed cell …

Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions
and regulates many cellular processes, including growth, proliferation, survival …

Due to the lack of success in small-diameter (< 6 mm) prosthetic vascular grafts, a variety of
strategies have evolved utilizing a tissue-engineering approach. Much of this work has …

For years intensive research has been done to improve the hemocompatibility of blood
contacting vascular devices. Despite the enormous progress in physicochemical surface …