Oxidative stress and cardiovascular risk: obesity, diabetes, smoking, and pollution: part 3 of a 3-part series

B Niemann, S Rohrbach, MR Miller, DE Newby… - Journal of the American …, 2017 - jacc.org
Oxidative stress occurs whenever the release of reactive oxygen species (ROS) exceeds
endogenous antioxidant capacity. In this paper, we review the specific role of several …

Health effects of particulate air pollution: a review of epidemiological evidence

R Rückerl, A Schneider, S Breitner, J Cyrys… - Inhalation …, 2011 - Taylor & Francis
FEF25–75, forced expiratory flow at 25–75% of vital capacity; FEV1, forced expiratory
volume in 1 second; FMD, flow-mediated dilatation; FVC, forced vital capacity; GIS …

Platelet activation and atherothrombosis

G Davì, C Patrono - New England Journal of Medicine, 2007 - Mass Medical Soc
This review of the role of platelets in atherothrombosis illuminates the surprisingly numerous
activities of these tiny, anucleate cells and stresses their participation in the inflammatory …

Systemic effects of smoking

DG Yanbaeva, MA Dentener, EC Creutzberg… - Chest, 2007 - Elsevier
Smoking is one of the major lifestyle factors influencing the health of human beings. Life-
long cigarette smokers have a higher prevalence of common diseases such as …

The biology behind the atherothrombotic effects of cigarette smoke

A Csordas, D Bernhard - Nature Reviews Cardiology, 2013 - nature.com
Cigarette smoke is an aerosol that contains> 4,000 chemicals, including nicotine, carbon
monoxide, acrolein, and oxidant compounds. Exposure to cigarette smoke induces multiple …

Cardiovascular disease in COPD: mechanisms

JD Maclay, W MacNee - Chest, 2013 - Elsevier
It is now well established that cardiovascular disease contributes significantly to both
morbidity and mortality in COPD. Shared risk factors for cardiovascular disease and COPD …

Diesel exhaust inhalation increases thrombus formation in man

AJ Lucking, M Lundback, NL Mills… - European heart …, 2008 - academic.oup.com
Aims Although the mechanism is unclear, exposure to traffic-derived air pollution is a trigger
for acute myocardial infarction (MI). The aim of this study is to investigate the effect of diesel …

Increased platelet activation in patients with stable and acute exacerbation of COPD

JD Maclay, DA McAllister, S Johnston, J Raftis… - Thorax, 2011 - thorax.bmj.com
Rationale Chronic obstructive pulmonary disease (COPD) is associated with systemic
inflammation and cardiovascular disease. Interaction between inflammatory cells and …

Inflammation in Carotid Atherosclerotic Plaque: A Dynamic Contrast-enhanced MR Imaging Study1

WS Kerwin, KD O'Brien, MS Ferguson, N Polissar… - Radiology, 2006 - pubs.rsna.org
Purpose: To prospectively evaluate if there is an association between plaque enhancement
at magnetic resonance (MR) imaging and proinflammatory cardiovascular risk factors and …

Aortic wall inflammation predicts abdominal aortic aneurysm expansion, rupture, and need for surgical repair

MA3RS Study Investigators - Circulation, 2017 - Am Heart Assoc
Background: Ultrasmall superparamagnetic particles of iron oxide (USPIO) detect cellular
inflammation on magnetic resonance imaging (MRI). In patients with abdominal aortic …