Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal
inflammation caused by an odontogenic infection eventually leads to bone loss …

Bone tissue destruction leads to severe pain, physical flaws, and loss of motility. Bone repair
using biocompatible and osteo-inductive scaffolds is regarded as a viable and potential …

The repair of large segmental bone defects remains a big challenge due to limited self-
healing capacity of bone. Digging into the structure and composition of natural long bone let …

For guided bone regeneration (GBR) in clinical orthopedics, the importance of a suitable
scaffold which can provide the space needed for bone regeneration and simultaneously …

The guided bone regeneration (GBR) membranes currently used in clinics are usually
compromised by their limited osteogenic induction potential. In this study, we fabricate a …

The periosteum plays a vital role in the regeneration of critical‐size bone defects and highly
comminuted fractures, promoting the differentiation of osteoblasts, accelerating the …

The presence of periosteum can greatly affect the repair of a bone fracture. An artificial
periosteum imitates the biological function of natural periosteum, which is capable of …

Recruiting endogenous bone marrow mesenchymal stem cells (BMSCs) in vivo to bone
defect sites shows great promise in cell therapies for bone tissue engineering, which tackles …

The periosteum plays an indispensable role in immunomodulation and osteogenesis during
bone regeneration. The natural periosteum has a hierarchical structure, in which the outer …

Periosteum possesses unique characteristics such as anisotropic structure and superior
osteogenic and angiogenic ability, which plays vital roles in the formation, remodeling and …