Paternal factors contributing to embryo quality

S Colaco, D Sakkas - Journal of assisted reproduction and genetics, 2018 - Springer
Purpose Advancing maternal and paternal age leads to a decrease in fertility, and hence,
many infertile couples opt for assisted reproductive technologies [ART] to achieve biological …

The sins of our forefathers: paternal impacts on de novo mutation rate and development

RJ Aitken, GN De Iuliis, B Nixon - Annual Review of Genetics, 2020 - annualreviews.org
Spermatogonial stem cells (SSCs) are generally characterized by excellent DNA
surveillance and repair, resulting in one of the lowest spontaneous mutation rates in the …

Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment …

R West, A Coomarasamy, L Frew, R Hutton… - Human …, 2022 - academic.oup.com
STUDY QUESTION What effects did treatment using hyaluronic acid (HA) binding/selection
prior to ICSI have on clinical outcomes in the Hyaluronic Acid Binding sperm Selection …

Fatherhood and sperm DNA damage in testicular cancer patients

D Paoli, F Pallotti, A Lenzi, F Lombardo - Frontiers in endocrinology, 2018 - frontiersin.org
Testicular cancer (TC) is one of the most treatable of all malignancies and the management
of the quality of life of these patients is increasingly important, especially with regard to their …

Paternal alcohol consumption has intergenerational consequences in male offspring

MY Cambiasso, L Gotfryd, MG Stinson, S Birolo… - Journal of Assisted …, 2022 - Springer
Purpose Alcoholism is a heterogeneous set of disorders caused by ethanol intake. Harmful
effects of paternal consumption on the offspring are poorly explored and not fully …

How 1 h of abstinence improves sperm quality and increases embryo euploidy rate after PGT-A: A study on 106 sibling biopsied blastocysts

F Scarselli, E Cursio, S Muzzì, V Casciani… - Journal of Assisted …, 2019 - Springer
Purpose The aim of our study was to evaluate the influence of different ejaculatory
abstinence time frames (several days versus 1 h) on semen parameters, blastocysts ploidy …

Does a very short length of abstinence improve assisted reproductive technique outcomes in infertile patients with severe oligo-asthenozoospermia?

F Barbagallo, AE Calogero, RA Condorelli… - Journal of Clinical …, 2021 - mdpi.com
In recent years, a growing number of studies seem to support the beneficial effects of a very
short abstinence period on sperm parameters, especially in patients with oligo …

The effect of human sperm chromatin maturity on ICSI outcomes

K Gill, A Rosiak, D Gaczarzewicz, J Jakubik… - Human cell, 2018 - Springer
Because sperm chromatin may play a key role in reproductive success, we verify the
associations between sperm chromatin abnormalities, embryo development and the ability …

Sperm histone modifications may predict success in human assisted reproduction: a pilot study

MY Cambiasso, M Romanato, L Gotfryd… - Journal of Assisted …, 2024 - Springer
Purpose Currently, assisted reproduction clinics employ various sperm selection techniques
to identify the best sperm for fertilization. However, these techniques may not assess crucial …

Human sperm morphology as a marker of its nuclear quality and epigenetic pattern

M Bendayan, L Caceres, E Saïs… - Cells, 2022 - mdpi.com
Background: Human sperm chromatin condensation is a sum of epigenetic events that
allows for the near-complete replacement of histones with protamines. Under high …