Topical drug delivery: History, percutaneous absorption, and product development

MS Roberts, HS Cheruvu, SE Mangion… - Advanced drug delivery …, 2021 - Elsevier
Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …

[HTML][HTML] Nanoparticles for topical application in the treatment of skin dysfunctions—an overview of dermo-cosmetic and dermatological products

M Raszewska-Famielec, J Flieger - International Journal of Molecular …, 2022 - mdpi.com
Nanomaterials (NM) arouse interest in various fields of science and industry due to their
composition-tunable properties and the ease of modification. They appear currently as …

Nanoparticles skin absorption: New aspects for a safety profile evaluation

FL Filon, M Mauro, G Adami, M Bovenzi… - Regulatory Toxicology …, 2015 - Elsevier
Nanoparticles (NPs) skin absorption is a wide issue, which needs to be better understood.
The attempt of this review is to summarize the scientific evidence concerning open …

Topical and cutaneous delivery using nanosystems

MS Roberts, Y Mohammed, MN Pastore… - Journal of controlled …, 2017 - Elsevier
The goal of topical and cutaneous delivery is to deliver therapeutic and other substances to
a desired target site in the skin at appropriate doses to achieve a safe and efficacious …

Nanoparticles and microparticles for skin drug delivery

TW Prow, JE Grice, LL Lin, R Faye, M Butler… - Advanced drug delivery …, 2011 - Elsevier
Skin is a widely used route of delivery for local and systemic drugs and is potentially a route
for their delivery as nanoparticles. The skin provides a natural physical barrier against …

Nanoparticles for topical drug delivery: Potential for skin cancer treatment

V Krishnan, S Mitragotri - Advanced Drug Delivery Reviews, 2020 - Elsevier
Nanoparticles offer new opportunities for the treatment of skin diseases. The barrier function
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …

Selective follicular targeting by modification of the particle sizes

A Patzelt, H Richter, F Knorr, U Schäfer, CM Lehr… - Journal of controlled …, 2011 - Elsevier
Hair follicles represent interesting target sites for topically applied substances such as
topical vaccinations or agents used in the field of regenerative medicine. In recent years, it …

Recent advances in follicular drug delivery of nanoparticles

A Patzelt, J Lademann - Expert opinion on drug delivery, 2020 - Taylor & Francis
Introduction: The improvement of percutaneous absorption represents a clear
dermatopharmaceutical aim. Recently, the hair follicle was recognized to be an important …

[HTML][HTML] Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders

Y Gu, Q Bian, Y Zhou, Q Huang, J Gao - Asian Journal of Pharmaceutical …, 2022 - Elsevier
The hair follicle is not only a critical penetration route in percutaneous absorption but also
has been recognized to be a target for hair follicle-associated disorders, such as …

Chitosan nanoparticles for targeting and sustaining minoxidil sulphate delivery to hair follicles

BN Matos, TA Reis, T Gratieri, GM Gelfuso - International journal of …, 2015 - Elsevier
This work developed minoxidil sulphate-loaded chitosan nanoparticles (MXS-NP) for
targeted delivery to hair follicles, which could sustain drug release and improve the topical …