Immune responses during COVID-19 infection

C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …

Angiotensin II type I receptor (AT1R): the gate towards COVID-19-associated diseases

G El-Arif, S Khazaal, A Farhat, J Harb, C Annweiler… - Molecules, 2022 - mdpi.com
The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike
glycoprotein to its cellular receptor, the angiotensin-converting enzyme 2 (ACE2), causes its …

Role of angiotensin II in cardiovascular diseases: Introducing bisartans as a novel therapy for coronavirus 2019

J Swiderski, LK Gadanec, V Apostolopoulos, GJ Moore… - Biomolecules, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the main contributors to global morbidity and mortality.
Major pathogenic phenotypes of CVDs include the development of endothelial dysfunction …

Antibodies against angiotensin II type 1 and endothelin A receptors: relevance and pathogenicity

MC Philogene, T Johnson, AJ Vaught, S Zakaria… - Human immunology, 2019 - Elsevier
Antibodies against two G-protein coupled receptors (GPCRs), angiotensin II type 1 receptor
(AT1R) and endothelin A receptor (ETAR) are among a growing number of autoantibodies …

SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly

A Onnis, E Andreano, C Cassioli, F Finetti… - Journal of Experimental …, 2022 - rupress.org
CTL-mediated killing of virally infected or malignant cells is orchestrated at the immune
synapse (IS). We hypothesized that SARS-CoV-2 may target lytic IS assembly to escape …

Beauty and the beast: host microRNA-155 versus SARS-CoV-2

KI Papadopoulos, A Papadopoulou, TC Aw - Human Cell, 2023 - Springer
Severe acute respiratory coronavirus 2 (SARS-CoV-2) infection in the young and healthy
usually results in an asymptomatic or mild viral syndrome, possibly through an erythropoietin …

[HTML][HTML] Angiotensin II type 1 receptor antibodies in kidney transplantation: an evidence-based comprehensive review

BM Sorohan, G Ismail, N Leca, D Tacu, B Obrișcă… - Transplantation …, 2020 - Elsevier
Angiotensin II type 1 receptor antibodies (AT1R-Ab) are among the most investigated types
of non-HLA antibodies in kidney transplantation. Our aim is to provide an update regarding …

Adaptive and maladaptive roles of different angiotensin receptors in the development of cardiac hypertrophy and heart failure

SK Bhullar, NS Dhalla - Canadian Journal of Physiology and …, 2023 - cdnsciencepub.com
Angiotensin II (Ang II) is formed by the action of angiotensin-converting enzyme (ACE) in the
renin–angiotensin system. This hormone is known to induce cardiac hypertrophy and heart …

Metabolic syndrome and aberrant immune responses to viral infection and vaccination: Insights from small animal models

E Geerling, M Hameed, J Weger-Lucarelli… - Frontiers in …, 2022 - frontiersin.org
This review outlines the propensity for metabolic syndrome (MetS) to induce elevated
disease severity, higher mortality rates post-infection, and poor vaccination outcomes for …

Does angiotensin II peak in response to SARS-CoV-2?

LL Xavier, PFR Neves, LV Paz, LT Neves… - Frontiers in …, 2021 - frontiersin.org
Human infection by the SARS-CoV-2 is causing the current COVID-19 pandemic. With the
growing numbers of cases and deaths, there is an urgent need to explore …