Multi Layered Omics Approaches Reveal Glia Specific Alterations in Alzheimer's Disease: A Systematic Review and Future Prospects

Ö İş, Y Min, X Wang, SR Oatman, A Abraham Daniel… - Glia, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative dementia with multi‐
layered complexity in its molecular etiology. Multiple omics‐based approaches, such as …

ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer's disease through BDNF/NGFR signaling

H Tayran, E Yilmaz, P Bhattarai, Y Min, X Wang, Y Ma… - Cell genomics, 2024 - cell.com
Genetic variants in ABCA7, an Alzheimer's disease (AD)-associated gene, elevate AD risk,
yet its functional relevance to the etiology is unclear. We generated a CRISPR-Cas9 …

Microvascular and cellular dysfunctions in Alzheimer's disease: An integrative analysis perspective

M Li, X Hao, Z Hu, J Tian, J Shi, D Ma, M Guo, S Li… - Scientific Reports, 2024 - nature.com
Alzheimer's disease (AD) is the most common cause of dementia, characterized by memory
loss, cognitive decline, personality changes, and various neurological symptoms. The role of …

Proteomic analysis and experimental validation reveal the blood–brain barrier protective of Huanshaodan in the treatment of SAMP8 mouse model of Alzheimer's …

Y Su, N Liu, P Wang, C Shang, R Sun, J Ma, Z Li… - Chinese Medicine, 2024 - Springer
Background Huanshaodan (HSD) is a Chinese Herbal Compound which has a definite
clinical effect on Alzheimer's disease (AD), however, the underlying mechanism remains …

Modelo domótico para necesidades de pacientes con Alzheimer mediante el monitoreo, asistencia y notificación personalizada

KE Guamán Aime - 2024 - dspace.ups.edu.ec
Esta investigación aborda el diseño de un modelo domótico para pacientes con Alzheimer,
con el objetivo de mejorar su seguridad y calidad de vida mediante tecnologías basadas en …