Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

Oral direct-acting agent therapy for hepatitis C virus infection: a systematic review

O Falade-Nwulia, C Suarez-Cuervo… - Annals of internal …, 2017 - acpjournals.org
Background: Rapid improvements in hepatitis C virus (HCV) therapy have led to the
approval of multiple oral direct-acting antiviral (DAA) regimens by the US Food and Drug …

EASL recommendations on treatment of hepatitis C 2016

European Association for The Study of The Liver - Journal of hepatology, 2017 - Elsevier
Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …

EASL recommendations on treatment of hepatitis C 2018

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2018 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

[HTML][HTML] EASL recommendations on treatment of hepatitis C 2015

European Association For The Study Of The Liver - Journal of hepatology, 2015 - Elsevier
Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …

[PDF][PDF] Hepatitis C guidance: AASLD‐IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus

AASLD/IDSA HCV Guidance Panel, RT Chung… - …, 2015 - Wiley Online Library
The pace of hepatitis C virus (HCV) drug development in recent years has accelerated
dramatically. For patients to benefit from these impressive advances, practitioners need …

Extrahepatic morbidity and mortality of chronic hepatitis C

F Negro, D Forton, A Craxì, MS Sulkowski, JJ Feld… - Gastroenterology, 2015 - Elsevier
Chronic hepatitis C virus (HCV) infection is associated with several extrahepatic
manifestations. Patients with HCV may develop mixed cryoglobulinemia and its sequelae …

[HTML][HTML] From non-A, non-B hepatitis to hepatitis C virus cure

JM Pawlotsky, JJ Feld, S Zeuzem, JH Hoofnagle - Journal of hepatology, 2015 - Elsevier
The hepatitis C virus (HCV) was discovered in the late 1980s. Interferon (IFN)-α was
proposed as an antiviral treatment for chronic hepatitis C at about the same time. Successive …

[HTML][HTML] Efficacy of direct-acting antiviral combination for patients with hepatitis C virus genotype 1 infection and severe renal impairment or end-stage renal disease

PJ Pockros, KR Reddy, PS Mantry, E Cohen, M Bennett… - Gastroenterology, 2016 - Elsevier
Background & Aims Although hepatitis C virus (HCV) infection is common in patients with
end-stage renal disease, highly efficacious, well-tolerated, direct-acting antiviral regimens …

An interferon-free antiviral regimen for HCV after liver transplantation

PY Kwo, PS Mantry, E Coakley, HS Te… - … England Journal of …, 2014 - Mass Medical Soc
Background Hepatitis C virus (HCV) infection is the leading indication for liver
transplantation worldwide, and interferon-containing regimens are associated with low …