SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

AD Proal, MB VanElzakker, S Aleman, K Bach… - Nature …, 2023 - nature.com
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …

Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks

AK Keita, FR Koundouno, M Faye, A Düx, J Hinzmann… - Nature, 2021 - nature.com
Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the
country faced a new outbreak—between 14 February and 19 June 2021—near the …

Ebola virus disease

D Malvy, AK McElroy, H de Clerck, S Günther… - The Lancet, 2019 - thelancet.com
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic
disease in man and great apes. Four species of ebolaviruses have been identified in west or …

Ebola

H Feldmann, A Sprecher… - New England Journal of …, 2020 - Mass Medical Soc
Ebola | New England Journal of Medicine Skip to main content The New England Journal of
Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …

Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors

J Liu, JC Trefry, AM Babka, CW Schellhase… - Science translational …, 2022 - science.org
Effective therapeutics have been developed against acute Ebola virus disease (EVD) in both
humans and experimentally infected nonhuman primates. However, the risk of viral …

Joint external evaluation of the International Health Regulation (2005) capacities: current status and lessons learnt in the WHO African region

A Talisuna, AA Yahaya, SC Rajatonirina, M Stephen… - BMJ global …, 2019 - gh.bmj.com
The International Health Regulations (IHR, 2005) are an essential vehicle for addressing
global health security. Here, we report the IHR capacities in the WHO African from …

Ebola virus antibody decay–stimulation in a high proportion of survivors

C Adaken, JT Scott, R Sharma, R Gopal, S Dicks… - Nature, 2021 - nature.com
Neutralizing antibody function provides a foundation for the efficacy of vaccines and
therapies,–. Here, using a robust in vitro Ebola virus (EBOV) pseudo-particle infection assay …

Recent successes in therapeutics for Ebola virus disease: no time for complacency

PL Iversen, CD Kane, X Zeng, RG Panchal… - The Lancet Infectious …, 2020 - thelancet.com
The PALM trial in the Democratic Republic of the Congo identified a statistically significant
survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute …

Viral genomics in Ebola virus research

N Di Paola, M Sanchez-Lockhart, X Zeng… - Nature Reviews …, 2020 - nature.com
Filoviruses such as Ebola virus continue to pose a substantial health risk to humans.
Advances in the sequencing and functional characterization of both pathogen and host …