Application of exosomes as liquid biopsy in clinical diagnosis

B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …

Urinary MicroRNAs as biomarkers of urological cancers: a systematic review

A Aveta, S Cilio, R Contieri, G Spena… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) are emerging as biomarkers for the detection and prognosis of
cancers due to their inherent stability and resilience. To summarize the evidence regarding …

Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

Bladder cancer diagnosis and follow-up: the current status and possible role of extracellular vesicles

E Oeyen, L Hoekx, S De Wachter, M Baldewijns… - International journal of …, 2019 - mdpi.com
Diagnostic methods currently used for bladder cancer are cystoscopy and urine cytology.
Cystoscopy is an invasive tool and has low sensitivity for carcinoma in situ. Urine cytology is …

The role of extracellular vesicles in cancer: cargo, function, and therapeutic implications

J Jabalee, R Towle, C Garnis - Cells, 2018 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound structures
that play key roles in intercellular communication. EVs are potent regulators of …

[HTML][HTML] Urine biopsy technologies: Cancer and beyond

CK Chen, J Liao, MS Li, BL Khoo - Theranostics, 2020 - ncbi.nlm.nih.gov
Since the discovery of circulating tumor cells in 1869, technological advances in the study of
biomarkers from liquid biopsy have made it possible to diagnose disease in a less invasive …

Diagnosis of hyperacute and acute ischaemic stroke: the potential utility of exosomal MicroRNA-21-5p and MicroRNA-30a-5p

W Wang, DB Li, RY Li, X Zhou, DJ Yu, XY Lan… - Cerebrovascular …, 2018 - karger.com
Background: Early and accurate diagnosis of ischaemic stroke (IS) requires the use of an
optimized biomarker. Exosomal microRNAs have the potential to serve as biomarkers owing …

Role of exosomal miRNA in bladder cancer: a promising liquid biopsy biomarker

XM Piao, EJ Cha, SJ Yun, WJ Kim - International journal of molecular …, 2021 - mdpi.com
Bladder cancer (BCa) is the most prevalent neoplasia of the urinary tract. Unfortunately,
limited improvements in effective BCa management have meant that it remains a …

Tumor-derived exosomal non-coding RNAs as diagnostic biomarkers in cancer

N Ebrahimi, F Faghihkhorasani, SS Fakhr… - Cellular and Molecular …, 2022 - Springer
Almost all clinical oncologists agree that the discovery of reliable, accessible, and non-
invasive biomarkers is necessary to decrease cancer mortality. It is possible to employ …

Urinary biomarkers in bladder cancer: where do we stand and potential role of extracellular vesicles

MC Oliveira, HR Caires, MJ Oliveira, A Fraga… - Cancers, 2020 - mdpi.com
Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved
in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and …