The free-living flatworm Macrostomum lignano

J Wudarski, B Egger, SA Ramm, L Schärer, P Ladurner… - EvoDevo, 2020 - Springer
Macrostomum lignano is a free-living flatworm that is emerging as an attractive experimental
animal for research on a broad range of biological questions. One feature setting it apart …

Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano

J Wudarski, D Simanov, K Ustyantsev… - Nature …, 2017 - nature.com
Regeneration-capable flatworms are informative research models to study the mechanisms
of stem cell regulation, regeneration, and tissue patterning. However, the lack of …

[HTML][HTML] The regenerative flatworm Macrostomum lignano, a model organism with high experimental potential

S Mouton, J Wudarski, M Grudniewska… - … International journal of …, 2018 - ncbi.nlm.nih.gov
Understanding the process of regeneration has been one of the longstanding scientific aims,
from a fundamental biological perspective, as well as within the applied context of …

Evolutionary analysis of species-specific duplications in flatworm genomes

M Langleib, J Calvelo, A Costábile, E Castillo… - Molecular Phylogenetics …, 2024 - Elsevier
Platyhelminthes, also known as flatworms, is a phylum of bilaterian invertebrates infamous
for their parasitic representatives. The classes Cestoda, Monogenea, and Trematoda …

Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano

M Grudniewska, S Mouton, D Simanov, F Beltman… - Elife, 2016 - elifesciences.org
The regeneration-capable flatworm Macrostomum lignano is a powerful model organism to
study the biology of stem cells in vivo. As a flatworm amenable to transgenesis, it …

Frequent origins of traumatic insemination involve convergent shifts in sperm and genital morphology

JN Brand, LJ Harmon, L Schärer - Evolution Letters, 2022 - academic.oup.com
Traumatic insemination is a mating behavior during which the (sperm) donor uses a
traumatic intromittent organ to inject an ejaculate through the epidermis of the (sperm) …

New insights into the karyotype evolution of the free-living flatworm Macrostomum lignano (Platyhelminthes, Turbellaria)

KS Zadesenets, L Schärer, NB Rubtsov - Scientific Reports, 2017 - nature.com
The free-living flatworm Macrostomum lignano is a model organism for evolutionary and
developmental biology studies. Recently, an unusual karyotypic diversity was revealed in …

A phylogenetically informed search for an alternative Macrostomum model species, with notes on taxonomy, mating behavior, karyology, and genome size

L Schärer, JN Brand, P Singh… - Journal of Zoological …, 2020 - Wiley Online Library
The free‐living flatworm Macrostomum lignano is used as a model in a range of research
fields—including aging, bioadhesion, stem cells, and sexual selection—culminating in the …

[HTML][HTML] Organ specific gene expression in the regenerating tail of Macrostomum lignano

B Lengerer, J Wunderer, R Pjeta, G Carta, D Kao… - Developmental …, 2018 - Elsevier
Temporal and spatial characterization of gene expression is a prerequisite for the
understanding of cell-, tissue-, and organ-differentiation. In a multifaceted approach to …

[HTML][HTML] Large-scale phylogenomics of the genus Macrostomum (Platyhelminthes) reveals cryptic diversity and novel sexual traits

JN Brand, G Viktorin, RAW Wiberg, C Beisel… - Molecular Phylogenetics …, 2022 - Elsevier
Free-living flatworms of the genus Macrostomum are small and transparent animals,
representing attractive study organisms for a broad range of topics in evolutionary …