COVID‐19 is a pandemic disease caused by the new coronavirus SARS‐CoV‐2 that mostly
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …

Viral pathogens often exploit host cell regulatory and signaling pathways to ensure an
optimal environment for growth and survival. Several studies have suggested that 5 …

Human noroviruses (HuNoVs) are the leading cause of viral gastroenteritis worldwide; yet
currently, no vaccines or FDA-approved antiviral drugs are available to counter these …

Interferon (IFN) regulatory factor 3 (IRF3) is a transcription factor activated by
phosphorylation in the cytoplasm of a virus-infected cell; by translocating to the nucleus, it …

The type-I interferon (IFN) system represents the first line of defense against viral pathogens.
Recognition of the virus initiates complex signaling pathways that result in the transcriptional …

Virus-infected cells trigger a robust innate immune response and facilitate virus replication.
Here, we review the role of autophagy in virus infection, focusing on both pro-viral and anti …

Molecular responses to influenza A virus (IAV) infections vary between mammalian species.
To identify conserved and species-specific molecular responses, we perform a comparative …

Many viruses activate cellular autophagy in infected cells to facilitate their replication.
Recently, we identified an interferon (IFN)-stimulated gene (ISG) Tudor domain containing 7 …

In humans, TDRD7 (tudor domain containing 7) mutations lead to a syndrome combining
congenital cataracts (CCs) and non-obstructive azoospermia (NOA), characterized by …

Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing
mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon …