[HTML][HTML] Targeting the complement system for the management of retinal inflammatory and degenerative diseases
The retina, an immune privileged tissue, has specialized immune defense mechanisms
against noxious insults that may exist in diseases such as age-related macular degeneration …
against noxious insults that may exist in diseases such as age-related macular degeneration …
[HTML][HTML] Progress in the genetics of uveitis
Uveitis is the most common form of intraocular inflammatory disease and is a significant
cause of visual impairment worldwide. Aetiologically, uveitis can also be classified into …
cause of visual impairment worldwide. Aetiologically, uveitis can also be classified into …
Genetics of ankylosing spondylitis
PC Robinson, MA Brown - Molecular immunology, 2014 - Elsevier
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and
sacroiliac joints. It causes significant disability and is associated with a number of other …
sacroiliac joints. It causes significant disability and is associated with a number of other …
Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis
PC Robinson, TAM Claushuis, A Cortes… - Arthritis & …, 2015 - Wiley Online Library
Objective To use high‐density genotyping to investigate the genetic associations of acute
anterior uveitis (AAU) in patients with and those without ankylosing spondylitis (AS) …
anterior uveitis (AAU) in patients with and those without ankylosing spondylitis (AS) …
The risk assessment of uveitis after COVID‐19 diagnosis: A multicenter population‐based study
Reports on uveitis after COVID‐19 have been limited. Our objective was to examine the risk
of uveitis among COVID‐19 patients. This was a retrospective cohort study based on the …
of uveitis among COVID‐19 patients. This was a retrospective cohort study based on the …
HLA-B27 anterior uveitis: immunology and immunopathology
D Wakefield, W Yates, S Amjadi… - Ocular immunology and …, 2016 - Taylor & Francis
Acute anterior uveitis (AAU) is the commonest type of uveitis and HLA-B27 AAU is the most
frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent …
frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent …
[HTML][HTML] Lack of association of C3 gene with uveitis: additional insights into the genetic profile of uveitis regarding complement pathway genes
MM Yang, J Wang, L Dong, DJ Kong, Y Teng, P Liu… - Scientific reports, 2017 - nature.com
Uveitis is a devastating ocular disease that causes blindness. Our previous studies have
achieved great advancements in depicting the genetic profiles of uveitis regarding …
achieved great advancements in depicting the genetic profiles of uveitis regarding …
Association between interleukin-27 gene polymorphisms and susceptibility to allergic rhinitis
Y Shen, XD Yuan, D Hu, X Ke, XQ Wang, GH Hu… - Human immunology, 2014 - Elsevier
Objectives Allergic rhinitis (AR) is an inflammatory disorder of the upper airway. Interleukin-
27 (IL-27), a novel IL-12 family member, has recently been reported to play a role in some …
27 (IL-27), a novel IL-12 family member, has recently been reported to play a role in some …
[HTML][HTML] An updated advancement of bifunctional IL-27 in inflammatory autoimmune diseases
WD Xu, DC Wang, M Zhao, AF Huang - Frontiers in Immunology, 2024 - frontiersin.org
Interleukin-27 (IL-27) is a member of the IL-12 family. The gene encoding IL-27 is located at
chromosome 16p11. IL-27 is considered as a heterodimeric cytokine, which consists of …
chromosome 16p11. IL-27 is considered as a heterodimeric cytokine, which consists of …
[HTML][HTML] Influence of molecular genetics in Vogt-Koyanagi-Harada disease
Abstract Vogt-Koyanagi-Harada (VKH) disease is a systemic autoimmune disorder against
melanocytes. Recent studies have identified multiple genetic factors that might be …
melanocytes. Recent studies have identified multiple genetic factors that might be …