[HTML][HTML] Metformin ameliorates neuroinflammatory environment for neurons and astrocytes during in vitro and in vivo stroke and tobacco smoke chemical exposure …
Despite the protective nature of the blood-brain barrier (BBB) and brain-protecting tissues,
some types of CNS injury or stress can cause cerebral cytokine production and profound …
some types of CNS injury or stress can cause cerebral cytokine production and profound …
[HTML][HTML] A highly sensitive UPLC-MS/MS method for the quantification of the organic cation transporters' mediated metformin uptake and its inhibition in cells
G Bajraktari-Sylejmani, C Bay, L Gebauer, J Burhenne… - Molecules, 2024 - mdpi.com
Metformin is the gold standard substrate for evaluating potential inhibitors of the organic
cation transporters (OCTs). Here, we established a UPLC-MS/MS assay to quantify …
cation transporters (OCTs). Here, we established a UPLC-MS/MS assay to quantify …
Metformin finding its way into the central nervous system: Combating neurological diseases?
A Cignarella, Q Lin, M Bae - The Journal of Pharmacology …, 2025 - jpet.aspetjournals.org
Metformin (1, 1-dimethylbiguanide) is a widely used medication for treating type 2 diabetes
mellitus. Potential uses outside type 2 diabetes include other syndromes with accompanying …
mellitus. Potential uses outside type 2 diabetes include other syndromes with accompanying …