Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …

The pervasiveness and mortality associated with methamphetamine abuse have doubled
during the past decade, suggesting a possible worldwide substance use crisis. Epitomizing …

Methamphetamine (METH) is a potent stimulant that induces a euphoric state but also
causes cognitive impairment, neurotoxicity and neurodevelopmental deficits. Yet, the …

A non-targeted metabolomics-based approach is presented that enables the study of
pathways in response to drug action with the aim of defining the mode of action of …

Despite the progress in characterising the pharmacological profile of drugs of abuse, their
precise biochemical impact remains unclear. The metabolome reflects the multifaceted …

Metabolomic analysis provides a powerful new tool for studies of Drosophila physiology.
This approach allows investigators to detect thousands of chemical compounds in a single …

Background Ticks (Family Ixodidae) transmit a variety of disease causing agents to humans
and animals. The tick-borne flaviviruses (TBFs; family Flaviviridae) are a complex of viruses …

Phosphorylation is a phase II detoxification reaction that, among animals, occurs near
exclusively in insects, but the enzymes responsible have never been cloned or otherwise …

Methamphetamine (METH) is known to damage neurons and induce psychosis. It can also
induce apoptosis in seminiferous tubules and affect sperm quality. The present study was …

With substance use disorder rates rising, there is an urgent need for new and effective
treatment modalities. The utilization of nutrition services in addiction treatment has not been …