Fibroblast growth factors (FGFs) are a family of proteins possessing paracrine, autocrine, or
endocrine functions in a variety of biological processes, including embryonic development …

The use of genetically modified animals has been studied in scientific research over time as
a way to discover new treatments or even a cure for various diseases. Transgenic …

Prostate cancer (PCa) is the most common malignancy affecting men in the western world.
Although radical prostatectomy and radiation therapy can successfully treat PCa in the …

Background In recent times, anti-cancer treatments have focused on Fibroblast Growth
Factor (FGF) and Vascular-Endothelial Growth Factor (VEGF) pathway inhibitors so as to …

Delayed cancer progression in the ventral prostate of the Transgenic Adenocarcinoma of the
Mouse Prostate (TRAMP) model has been previously reported upon celecoxib and …

The aim of this study was to characterize the structural and molecular biology as well as
evaluate the immediate and late responses of prostatic cancer in the transgenic …

Dysregulation of the fibroblast growth factors/fibroblast growth factor receptor (FGF/FGFR)
pathway has been implicated in a wide range of human disorders and several members …

Purpose Benign prostate hyperplasia (BPH) is a common age-related chronic condition. Its
pathogenesis involves androgen imbalance, inflammation, oxidative stress, and …

Background Chronic inflammation has been implicated in cancer etiology and angiogenesis
is stimulated in this disease. In prostate, the crosstalk between malignant epithelial cells and …

BACKGROUND Prostate is highly affected by aging, which lead to inflammatory disorders
that can predispose to cancer development. Chemoprevention has emerged as a new …