Hypospadias is a congenital anomaly of the penis with an occurrence of approximately 1 in
200 boys, but the etiology of the majority of hypospadias has remained unknown. Numerous …

Background Hypospadias is a common congenital malformation of male external genitalia,
which mainly manifests as an abnormal urethral opening on the ventral side of the penis …

Hypospadias, which is characterised by the displacement of the urethral meatus from its
typical anatomical location in males, shows various degrees of severity. In this systematic …

Hypospadias is a common form of congenital atypical sex development that is often
associated with other congenital comorbidities. Many genes have been associated with the …

Objective The association between periconceptional parental exposure to endocrine-
disrupting chemicals (EDCs) and hypospadias remains inconclusive and controversial …

Background To study hypospadias as regard epidemiological risk factors and genetic
association with mutations in Steroid 5 alpha reductase type 2 genes. Materials This study …

Background CNV in KCTD13 has been identified to influence androgen receptor function via
its changes in gene dosage, which might contribute to hypospadias. However, there is lack …

Background The etiological mechanism of hypospadias is multifactorial and may be
heterogeneous by severity. To date, very limited analyses on proteome in hypospadias have …

Background and Objective: Mild hypospadias is a birth congenital condition characterized
by the relocation of the male urethral meatus from its typical anatomical position near the tip …

Purpose: Human chorionic gonadotropin stimulates fetal testosterone production and
contributes to normal development of male genitalia. Using population based data we …