Advances and Highlights of miRNAs in Asthma: Biomarkers for diagnosis and treatment

M Gil-Martínez, C Lorente-Sorolla, S Naharro… - International journal of …, 2023 - mdpi.com
Asthma is a heterogeneous inflammatory disease of the airways that causes breathing
difficulties, episodes of cough and wheezing, and in more severe cases can greatly diminish …

Specific therapy for T2 asthma

D Bagnasco, E Testino, S Nicola, L Melissari… - Journal of Personalized …, 2022 - mdpi.com
Asthma is a disease with high incidence and prevalence, and its severe form accounts for
approximately 10% of asthmatics. Over the last decade, the increasing knowledge of the …

[HTML][HTML] Dupilumab pharmacokinetics and effect on type 2 biomarkers in children with moderate-to-severe asthma

DJ Jackson, LB Bacharier, W Phipatanakul… - Annals of Allergy …, 2023 - Elsevier
Background Type 2 inflammation is common in children with asthma. Dupilumab, a human
antibody, blocks the signaling of interleukin-4 and-13, key and central drivers of type 2 …

Biologics and airway remodeling in asthma: early, late, and potential preventive effects

G Varricchi, R Poto, M Lommatzsch, G Brusselle… - Allergy, 2025 - Wiley Online Library
Although airway remodeling in severe and/or fatal asthma is stil considered irreversible, its
individual components as a cause of clinical symptoms and/or lung function changes remain …

Differential drug response in pulmonary arterial hypertension: The potential for precision medicine

E Miller, CUO Sampson, AA Desai… - Pulmonary …, 2023 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a rare, complex, and deadly cardiopulmonary
disease. It is characterized by changes in endothelial cell function and smooth muscle cell …

Utility of Kansas City Cardiomyopathy Questionnaire (KCCQ) in Assessing Quality of Life among Patients with Heart Failure Undergoing Exercise Training …

IE Sukosd, SA Pescariu, C Faur, AI Danila… - Diseases, 2024 - mdpi.com
This systematic review evaluates the effectiveness of the Kansas City Cardiomyopathy
Questionnaire (KCCQ) in assessing quality of life improvements among patients with heart …

Association between 25-hydroxy vitamin D and lung function (FEV1, FVC, FEV1/FVC) in children and adults with asthma: A systematic review

M Abi-Ayad, I Nedjar, N Chabni - Lung India, 2023 - journals.lww.com
Asthma is a chronic respiratory disease that poses significant individual, social, financial and
healthcare burdens. Physicians and researchers have recommended 25-hydroxy vitamin D …

Pulmonary Diseases in Older Patients: Understanding and Addressing the Challenges

PR Joshi - Geriatrics, 2024 - mdpi.com
As the global population ages, pulmonary diseases among older people have emerged as a
significant and growing public health concern. The increasing incidence of these conditions …

Effect of Dupilumab on Radiological Remission in Patients with Chronic Rhinosinusitis with Nasal Polyp: A One Step Forward Toward Clinical Remission

M Al-Ahmad, A Ali, HA Dawood… - Journal of Asthma and …, 2024 - Taylor & Francis
Background and Objectives While achieving complete radiological improvement in patients
with nasal polyps is often observed following surgical resection, the impact of biologic …

The assessment of dupilumab in children with moderate-to-severe asthma and comorbid type 2 inflammatory diseases

T Shi, S Wu, R Chen, Y Xie, G Yin, C He, C Liang… - BMC Pulmonary …, 2024 - Springer
Dupilumab inhibiting the signaling of interleukin (IL)-4 and IL-13 was recommended for the
treatment of severe asthma in children≥ 6 years old according to the Global Initiative for …