Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Cytokines function in many roles that are highly relevant to radiation research. This review
focuses on how cytokines are structurally organized, how they are induced by radiation, and …

Chemokines (chemo‐attractant cytokines) are a group of small proteins that act together with
their cell surface receptors, in development, normal physiology and immune responses, to …

Chemokines are signaling peptides which regulate cell trafficking and provide control of the
tissue-specific cell homing. In the skin, chemokines are secreted both by the resident cells …

Chemokines and their receptors control cell migration during development, immune system
responses, and in numerous diseases, including inflammation and cancer. The structural …

Connective tissues within the synovial joints are characterized by their dense extracellular
matrix and sparse cellularity. With injury or disease, however, tissues commonly experience …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Rheumatoid arthritis (RA) is a chronic inflammatory disease which leads to destruction of
joints. Current treatment modalities for RA either produce symptomatic relief (NSAIDs) or …

The abundance and type of immune cells in the tumor microenvironment (TME) significantly
influence immunotherapy and tumor progression. However, the role of immune cells in the …

Objective Proline–glycine–proline (PGP) has been shown to have chemotactic effects on
neutrophils via CXCR2 in several lung diseases. PGP is derived from collagen by the …