Chagas disease

JA Pérez-Molina, I Molina - The Lancet, 2018 - thelancet.com
Chagas disease is an anthropozoonosis from the American continent that has spread from
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …

Chagas cardiomyopathy—where do we stand after a hundred years?

A Biolo, AL Ribeiro, N Clausell - Progress in cardiovascular diseases, 2010 - Elsevier
A hundred years from its description, Chagas cardiomyopathy remains a challenging
disease. Although successful vector-control strategies have decreased the incidence of …

The epidemiology, clinical manifestations, and management of chagas heart disease

LH Malik, GD Singh, EA Amsterdam - Clinical cardiology, 2015 - Wiley Online Library
Chagas disease results from infection by the protozoan parasite Trypanosoma cruzi and is
endemic in Latin America. T cruzi is most commonly transmitted through the feces of an …

Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection

JC Villar, JG Perez, OL Cortes, A Riarte… - Cochrane Database …, 2014 - cochranelibrary.com
Background Prevention of chronic chagasic cardiomyopathy (CCC) by treating infected
populations with trypanocidal therapy (TT) remains a challenge. Despite a renewed …

β-Blocker therapy and mortality of patients with Chagas cardiomyopathy: a subanalysis of the REMADHE prospective trial

VS Issa, AF Amaral, FD Cruz, SMA Ferreira… - Circulation: Heart …, 2010 - Am Heart Assoc
Background—Peculiar aspects of Chagas cardiomyopathy raise concerns about efficacy
and safety of sympathetic blockade. We studied the influence of β-blockers in patients with …

Chagas heart disease: an update

LH Malik, GD Singh, EA Amsterdam - The American journal of medicine, 2015 - Elsevier
Chagas disease, also known as American trypanosomiasis, results from infection by the
protozoan Trypanosoma cruzi, and is a major cause of cardiac disease worldwide. Until …

[HTML][HTML] Comparison of outcome between Chagas cardiomyopathy and idiopathic dilated cardiomyopathy

AP Barbosa, A Cardinalli Neto, AP Otaviano… - Arquivos brasileiros de …, 2011 - SciELO Brasil
FUNDAMENTO: Pouco se sabe sobre o desfecho dos pacientes com cardiopatia chagásica,
em comparação aos pacientes com miocardiopatia dilatada idiopática na era …

Temporal trends in the contribution of Chagas cardiomyopathy to mortality among patients with heart failure

W Nadruz, L Gioli-Pereira, S Bernardez-Pereira… - Heart, 2018 - heart.bmj.com
Background Chagas cardiomyopathy (ChC) prevalence is decreasing in Brazil and medical
therapies for heart failure (HF) have improved in the last decade. Whether these changes …

Increases in [IP3]i aggravates diastolic [Ca2+] and contractile dysfunction in Chagas' human cardiomyocytes

A Mijares, R Espinosa, J Adams… - PLoS neglected tropical …, 2020 - journals.plos.org
Chagas cardiomyopathy is the most severe manifestation of human Chagas disease and
represents the major cause of morbidity and mortality in Latin America. We previously …

[HTML][HTML] Metabolomic insights in advanced cardiomyopathy of chronic chagasic and idiopathic patients that underwent heart transplant

RM de Oliveira, MUB Paiva, CRC Picossi… - Scientific …, 2024 - ncbi.nlm.nih.gov
Heart failure (HF) studies typically focus on ischemic and idiopathic heart diseases. Chronic
chagasic cardiomyopathy (CCC) is a progressive degenerative inflammatory condition …