Spatial navigation in older adults with mild cognitive impairment and dementia: A systematic review and meta-analysis

J Plácido, CAB de Almeida, JV Ferreira… - Experimental …, 2022 - Elsevier
In this systematic review and meta-analysis, we compared the spatial navigation
performance of older adults with mild cognitive impairment (MCI), Alzheimer's Disease (AD) …

Egocentric and allocentric spatial memory in mild cognitive impairment with real-world and virtual navigation tasks: A systematic review

C Tuena, V Mancuso… - Journal of …, 2021 - content.iospress.com
Background: Spatial navigation is the ability to estimate one's position on the basis of
environmental and self-motion cues. Spatial memory is the cognitive substrate underlying …

Predicting real world spatial disorientation in Alzheimer's disease patients using virtual reality navigation tests

V Puthusseryppady, S Morrissey, H Spiers, M Patel… - Scientific Reports, 2022 - nature.com
Spatial navigation impairments in Alzheimer's disease (AD) have been suggested to
underlie patients experiencing spatial disorientation. Though many studies have highlighted …

Know what? How digital technologies undermine learning and remembering

NS Baron - Journal of Pragmatics, 2021 - Elsevier
Are digital technologies affecting how we learn, what we know, and how we remember? We
examine three aspects of these questions: the impact of the internet on cognitive skills, the …

Different profiles of spatial navigation deficits in Alzheimer's disease biomarker-positive versus biomarker-negative older adults with amnestic mild cognitive …

M Laczó, L Martinkovic, O Lerch, JM Wiener… - Frontiers in aging …, 2022 - frontiersin.org
Background Spatial navigation impairment is a promising cognitive marker of Alzheimer's
disease (AD) that can reflect the underlying pathology. Objectives We assessed spatial …

Research progress on vestibular dysfunction and visual–spatial cognition in patients with Alzheimer's disease

Y Huang, J Xu, X Zhang, Y Liu, E Yu - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Alzheimer's disease (AD) or vestibular dysfunction may impair visual–spatial cognitive
function. Recent studies have shown that vestibular dysfunction is increasingly common in …

Assessing mild cognitive impairment using object‐location memory in immersive virtual environments

A Castegnaro, D Howett, A Li, E Harding… - …, 2022 - Wiley Online Library
Pathological changes in the medial temporal lobe (MTL) are found in the early stages of
Alzheimer's disease (AD) and aging. The earliest pathological accumulation of tau …

Systematic characterization of a non-transgenic Aβ1–42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice

R Jiménez-Herrera, A Contreras, S Djebari… - Biology of sex …, 2023 - Springer
Background The amyloid-β (A β) cascade is one of the most studied theories linked to AD. In
multiple models, A β accumulation and dyshomeostasis have shown a key role in AD onset …

Czech Brain Aging Study (CBAS): prospective multicentre cohort study on risk and protective factors for dementia in the Czech Republic

K Sheardova, M Vyhnalek, Z Nedelska, J Laczo… - BMJ open, 2019 - bmjopen.bmj.com
Purpose Identification of demographic, physical/physiological, lifestyle and genetic factors
contributing to the onset of dementia, specifically Alzheimer disease (AD), and …

Spatial navigation and visuospatial strategies in typical and atypical aging

M Laczó, JM Wiener, J Kalinova, V Matuskova… - Brain Sciences, 2021 - mdpi.com
Age-related spatial navigation decline is more pronounced in patients with mild cognitive
impairment (MCI) and Alzheimer's disease (AD) dementia. We used a realistic-looking …