MB Goldring, KB Marcu - Trends in molecular medicine, 2012 - cell.com
Osteoarthritis (OA) is a multifactorial disease subject to the effects of many genes and environmental factors. Alterations in the normal pattern of chondrocyte gene control in …
B Yang, H Guo, Y Zhang, L Chen, D Ying, S Dong - PloS one, 2011 - journals.plos.org
Chondrogenic differentiation of mesenchymal stem cells (MSCs) is accurately regulated by essential transcription factors and signaling cascades. However, the precise mechanisms …
TE Swingler, G Wheeler, V Carmont… - Arthritis & …, 2012 - Wiley Online Library
Objective To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a functional role in cartilage homeostasis. Methods The expression of miRNAs was measured …
MK Murphy, DJ Huey, JC Hu, KA Athanasiou - Stem cells, 2015 - academic.oup.com
Replacement of degenerated cartilage with cell-based cartilage products may offer a long- term solution to halt arthritis' degenerative progression. Chondrocytes are frequently used in …
In this study, we present an innovative strategy to reinforce 3D-printed hydrogel constructs for cartilage tissue engineering by formulating composite bioinks containing alginate and …
Lesions of articular cartilage do not heal spontaneously. One treatment strategy would be to make cartilage in the laboratory by directed chondrogenic differentiation of mesenchymal …
Osteoarthritis (OA) is the most common degenerative joint disease. One of the main pathogenic factors of OA is thought to be inflammation. Other factors associated with OA are …
YH Huang, HA Chen, CH Chen, HT Liao… - International Journal of …, 2023 - Elsevier
In this study, we fabricate squeezable cryogel microbeads as injectable scaffolds for minimum invasive delivery of chondrocytes for cartilage tissue engineering applications. The …
Y He, W Liu, L Guan, J Chen, L Duan… - BioMed research …, 2018 - Wiley Online Library
Scaffolds play an important role in tissue engineering and their structure and biocompatibility have great influence on cell behaviors. In this study, poly (l‐lactide‐co‐ε …