The importance of the excitatory amino acid transporter 3 (EAAT3)

WE Bjørn-Yoshimoto, SM Underhill - Neurochemistry international, 2016 - Elsevier
The neuronal excitatory amino acid transporter 3 (EAAT3) is fairly ubiquitously expressed in
the brain, though it does not necessarily maintain the same function everywhere. It is …

Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease

MG Bianchi, D Bardelli, M Chiu, O Bussolati - Cellular and Molecular Life …, 2014 - Springer
Excitatory amino acid transporters (EAATs) are high-affinity Na+-dependent carriers of major
importance in maintaining glutamate homeostasis in the central nervous system. EAAT3, the …

Autoimmunity and immune system dysregulation in schizophrenia: IgGs from sera of patients hydrolyze myelin basic protein

D Parshukova, LP Smirnova… - Journal of Molecular …, 2019 - Wiley Online Library
Several different theories of schizophrenia (SCZ) were discussed; the causes of this disease
are not yet clear. Using ELISA, it was shown that titers of autoantibodies against myelin …

Поиск биомаркеров и разработка фармакогенетических подходов к персонализированной терапии больных шизофренией

СА Иванова, ОЮ Федоренко, ЛП Смирнова… - … вестник психиатрии и …, 2013 - elibrary.ru
В статье представлены предварительные результаты исследований в области
трансляционной психиатрии. Основные направления связаны с поиском биомаркеров …

NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder

A Levchenko, NM Vyalova, T Nurgaliev… - Frontiers in …, 2020 - frontiersin.org
GSK3B, BDNF, NGF, NRG1, HTR2C, and PIP4K2A play important roles in molecular
mechanisms of psychiatric disorders. GSK3B occupies a central position in these molecular …

Catalase activity of IgG antibodies from the sera of healthy donors and patients with schizophrenia

EA Ermakov, LP Smirnova, NA Bokhan, AV Semke… - PLoS …, 2017 - journals.plos.org
We present first evidence showing that some electrophoretically homogeneous IgGs from
the sera of patients with schizophrenia (36.4%) and their Fab and F (ab) 2 fragments as well …

Association study indicates a protective role of phosphatidylinositol-4-phosphate-5-kinase against tardive dyskinesia

OY Fedorenko, AJM Loonen, F Lang… - International Journal …, 2015 - academic.oup.com
Background: Tardive dyskinesia is a disorder characterized by involuntary muscle
movements that occur as a complication of long-term treatment with antipsychotic drugs. It …

Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress

WJ Keune, DR Jones, Y Bultsma, L Sommer… - Science …, 2012 - science.org
Oxidative signaling and oxidative stress contribute to aging, cancer, and diseases resulting
from neurodegeneration. Pin1 is a proline isomerase that recognizes phosphorylated …

Intracellular signaling of the AMP-activated protein kinase

M Dërmaku-Sopjani, M Sopjani - … in protein chemistry and structural biology, 2019 - Elsevier
AMP-activated protein kinase (AMPK) is an essential cellular energy sensor that senses the
cellular energy status and maintains cellular energy balance. The AMPK coordinates …

Opening up new horizons for psychiatric genetics in the Russian Federation: moving toward a national consortium

OY Fedorenko, VE Golimbet, SА Ivanova… - Molecular …, 2019 - nature.com
We provide an overview of the recent achievements in psychiatric genetics research in the
Russian Federation and present genotype-phenotype, population, epigenetic, cytogenetic …