Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

In patients with compromised immunity, invasive fungal infections represent a significant
cause of mortality. Given the limited availability and drawbacks of existing first-line antifungal …

Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …

Traditional drug development is a long and expensive process with high rates of failure. This
has prompted the pharmaceutical industry to seek more efficient drug development …

ABSTRACT Bone‐on‐a‐chip (BOC) models that based on microfluidic technology have
widely applied to understand bone physiology and the pathogenesis of related diseases. In …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer characterised by
poor survival rates and an increasing global incidence. Advances in the staging and …

Abstract Microcarriers (MCs, typically 50–200 µm) are promising growth supports for high-
throughput cell expansion, with capability to overcome the limitations of surface area …

Disease models that can accurately recapitulate human pathophysiology during infection
and clinical response to antiviral therapeutics are still lacking, which represents a major …

Traditional goal of microfabrication was to limitedly construct nano-and micro-geometries on
silicon or quartz wafers using various semiconductor manufacturing technologies, such as …

Introduction: Organ-on-chips have become an effective platform for studying the physiology
of tissues and organs and for evaluating the safety and efficacy of drugs. In these systems …