Pharmaceutical chaperones and proteostasis regulators in the therapy of lysosomal storage disorders: current perspective and future promises

FE Mohamed, L Al-Gazali, F Al-Jasmi… - Frontiers in …, 2017 - frontiersin.org
Different approaches have been utilized or proposed for the treatment of lysosomal storage
disorders (LSDs) including enzyme replacement and hematopoietic stem cell transplant …

Mucopolysaccharidosis type II (Hunter syndrome): Clinical and biochemical aspects of the disease and approaches to its diagnosis and treatment

S Mohamed, QQ He, AA Singh, V Ferro - Advances in Carbohydrate …, 2020 - Elsevier
Abstract Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is a rare X-linked
lysosomal storage disease caused by mutations of the gene encoding the lysosomal …

[HTML][HTML] Checkpoint Inhibitor

S Mohamed, QQ He, AA Singh, V Ferro - checkpointinhibitor.com
Lysosomes are the organelles responsible for the intracellular degradation of
macromolecules such as oligosaccharides, glycolipids, proteins and glyco-proteins; their …

Synthèse d'aminocyclitols, inhibiteurs potentiels de glycosidases lysosomales, via des aldolases

FC Bres - 2010 - theses.hal.science
Les glycosidases sont des enzymes impliquées dans de nombreux processus biologiques.
Entre autres, elles sont responsables de la dégradation des déchets polysaccharidiques de …

[引用][C] 溶酶体贮积症的分子生物学机制

刘誉, 吴彬彬, 伍小华, 朱晓杨, 刘敏 - 暨南大学学报(自然科学与医学版), 2013