Benzodiazepines remain important therapeutic options in psychiatric practice

SL Dubovsky, D Marshall - Psychotherapy and Psychosomatics, 2022 - karger.com
Benzodiazepines and medications acting on benzodiazepine receptors that do not have a
benzodiazepine structure (z-drugs) have been viewed by some experts and regulatory …

Uncovering the hidden burden of pharmaceutical poisoning in high-income and low-middle-income countries: A scoping review

C Cowans, A Love, B Tangiisuran, SA Jacob - Pharmacy, 2023 - mdpi.com
Pharmaceutical poisoning is a significant global public health concern, causing
approximately 190,000 deaths annually. This scoping review aims to comprehensively map …

Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc …

AM Cardona-Acosta, OK Sial, LF Parise, T Gnecco… - Scientific Reports, 2023 - nature.com
Increased use of benzodiazepines in adolescents have been reported, with alprazolam
(ALP) being the most abused. Drug abuse during adolescence can induce changes with …

[HTML][HTML] Significant increase in deliberate self-poisonings among adolescents during the second year of the COVID-19 pandemic

A Koppen, IMJ Thoonen, CC Hunault… - Journal of Adolescent …, 2023 - Elsevier
Purpose The COVID-19 pandemic has been associated with a decline in mental health of
adolescents. The aim of this study was to analyze the rate of deliberate self-poisonings …

Nonmedical Use of Controlled Medications by Adolescents and Young Adults: Clinical Report

N Chadi, L Walker-Harding - Pediatrics, 2024 - publications.aap.org
Nonmedical prescription drug use (NMPDU), the use of controlled prescription medications
for purposes other than initially intended by the prescriber, is common among adolescents …

Mother's little helper turned a foe: Benzodiazepine use, misuse, and abuse

AM Cardona-Acosta, N Meisser, NI Vardeleon… - Progress in Neuro …, 2024 - Elsevier
Benzodiazepines are effective in managing anxiety and related disorders when used
properly (short-term). Their inappropriate use, however, carries significant risks, involving …

Trends in childhood poison exposures and fatalities: a retrospective secondary data analysis of the 2009–2019 US National Poison Data System annual reports

H Li, T Dodd-Butera, ML Beaman, MB Pritty… - Pediatric reports, 2021 - mdpi.com
Despite significant prevention efforts, childhood poison exposures remain a serious public
health challenge in the United States. This study aimed to assess annual trends of …

Comparison of dental benzodiazepine prescriptions from the US, England, and Australia from 2013 to 2018

L Teoh, W Thompson, CC Hubbard, W Gellad… - American journal of …, 2021 - Elsevier
Introduction Benzodiazepines contribute to substance use disorder and are often part of
polydrug abuse, most frequently with opioids. Although dental opioid prescribing differs …

Impact of a publicly-funded pharmacare program policy on benzodiazepine dispensing among children and youth: a population-based natural experiment

T Antoniou, D McCormack, S Kitchen, K Pajer… - BMC pediatrics, 2023 - Springer
Abstract Background In January 2018, the Government of Ontario, Canada, initiated a
universal pharmacare program (OHIP+) for all individuals aged 24 years and younger. In …

Adverse event profile of lorazepam: a real-world pharmacovigilance study using the FDA adverse event reporting system database

Z Su, Z Huang, X Chen, X Li - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction Anxiety diagnoses have surged recently during and after the COVID-19
pandemic. Lorazepam is widely recognized for its efficacy in treatment of anxiety, as well as …