Dendritic cells are powerful antigen-presenting cells that are essential for the priming of T
cell responses. In addition to providing T-cell-receptor ligands and co-stimulatory molecules …

The presentation of exogenous antigens on MHC class I molecules, known as cross-
presentation, is essential for the initiation of CD8+ T cell responses. In vivo, cross …

Macropinocytosis is a unique pathway of endocytosis characterised by the nonspecific
internalisation of large amounts of extracellular fluid, solutes and membrane in large …

Macropinocytosis is a regulated form of endocytosis that mediates the non‐selective uptake
of solute molecules, nutrients and antigens. It is an actin‐dependent process initiated from …

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides,
and load these peptides onto major histocompatibility complex (MHC) class I and II …

Dendritic cells are at the center of immune responses. They are defined by their ability to
sense the environment, take up and process antigen, migrate to secondary lymphoid …

Bone marrow–derived antigen-presenting cells (APCs) take up cell-associated antigens and
present them in the context of major histocompatibility complex (MHC) class I molecules to …

Exosomes are approximately 100-nm vesicles that consist of a lipid bilayer of cellular
membranes secreted in large quantities from various types of normal and disease-related …

As a population, dendritic cells (DC s) appear to be the best cross‐presenters of internalized
antigens on major histocompatibility complex class I molecules in the mouse. To do this, DC …