[HTML][HTML] The pilocarpine model of temporal lobe epilepsy

G Curia, D Longo, G Biagini, RSG Jones… - Journal of neuroscience …, 2008 - Elsevier
Understanding the pathophysiogenesis of temporal lobe epilepsy (TLE) largely rests on the
use of models of status epilepticus (SE), as in the case of the pilocarpine model. The main …

Sex differences in the epilepsies and associated comorbidities: implications for use and development of pharmacotherapies

CA Christian, DS Reddy, J Maguire, PA Forcelli… - Pharmacological …, 2020 - Elsevier
The epilepsies are common neurologic disorders characterized by spontaneous recurrent
seizures. Boys, girls, men, and women of all ages are affected by epilepsy and, in many …

[HTML][HTML] The pilocarpine model of epilepsy: what have we learned?

FA Scorza, RM Arida… - Anais da Academia …, 2009 - SciELO Brasil
The systemic administration of a potent muscarinic agonist pilocarpine in rats promotes
sequential behavioral and electrographic changes that can be divided into 3 distinct …

The influence of gonadal hormones on neuronal excitability, seizures, and epilepsy in the female

HE Scharfman, NJ MacLusky - Epilepsia, 2006 - Wiley Online Library
It is clear from both clinical observations of women, and research in laboratory animals, that
gonadal hormones exert a profound influence on neuronal excitability, seizures, and …

The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy

DS Reddy - Epilepsy research, 2009 - Elsevier
Catamenial epilepsy is a multifaceted neuroendocrine condition in which seizures are
clustered around specific points in the menstrual cycle, most often around perimenstrual or …

Sex differences in the neurobiology of epilepsy: a preclinical perspective

HE Scharfman, NJ MacLusky - Neurobiology of disease, 2014 - Elsevier
When all of the epilepsies are considered, sex differences are not always clear, despite the
fact that many sex differences are known in the normal brain. Sex differences in epilepsy in …

Mechanisms linking neurological disorders with reproductive endocrine dysfunction: insights from epilepsy research

CA Cutia, CA Christian-Hinman - Frontiers in Neuroendocrinology, 2023 - Elsevier
Gonadal hormone actions in the brain can both worsen and alleviate symptoms of
neurological disorders. Although neurological conditions and reproductive endocrine …

Sex and hormonal influences on seizures and epilepsy

J Velíšková, KA DeSantis - Hormones and behavior, 2013 - Elsevier
This article is part of a Special Issue" Hormones & Neurotrauma". Epilepsy is the third most
common chronic neurological disorder. Clinical and experimental evidence supports the …

Neuroendocrine aspects of catamenial epilepsy

DS Reddy - Hormones and behavior, 2013 - Elsevier
This article is part of a Special Issue" Hormones & Neurotrauma". This review describes the
neuroendocrinological aspects of catamenial epilepsy, a menstrual cycle-related seizure …

[HTML][HTML] Temporal lobe epilepsy and the BDNF receptor, TrkB

JO McNamara, HE Scharfman - 2012 - europepmc.org
Temporal lobe epilepsy (TLE) is a particularly devastating form of human epilepsy. The
disorder is progressive in a substantial fraction of patients, which is demonstrated by …