Investigation of stable and transient protein–protein interactions: past, present, and future

AG Ngounou Wetie, I Sokolowska, AG Woods… - …, 2013 - Wiley Online Library
This article presents an overview of the literature and a review of recent advances in the
analysis of stable and transient protein–protein interactions (PPI s) with a focus on their …

Identification of posttranslational modifications (PTMs) of proteins by mass spectrometry

R Aslebagh, KL Wormwood… - Advancements of mass …, 2019 - Springer
There are only 30,000 human genes, which, according to the central dogma from biology, it
means that there should be 30,000 mRNA and 30,000 proteins. However, there are at least …

Cancer secretomes and their place in supplementing other hallmarks of cancer

S Patel, AGN Wetie, CC Darie, BD Clarkson - Advancements of mass …, 2014 - Springer
The secretome includes all macromolecules secreted by cells, in particular conditions at
defined times, allowing cell–cell communication. Cancer cell secretomes that are altered …

l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia …

S Matsuura, H Katsumi, H Suzuki, N Hirai… - Pharmaceutics, 2018 - mdpi.com
l-cysteine (Cys)-and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM)
dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney …

Microencapsulation of Essential Oils Using Faba Bean Protein and Chia Seed Polysaccharides via Complex Coacervation Method

A Napiórkowska, A Szpicer, E Górska-Horczyczak… - Molecules, 2024 - mdpi.com
The aim of this study was to develop microcapsules containing juniper or black pepper
essential oils, using a combination of faba bean protein and chia seed polysaccharides (in …

Bottlenecks in proteomics: An update

D Channaveerappa, AG Ngounou Wetie… - Advancements of Mass …, 2019 - Springer
Mass spectrometry (MS) is the core for advanced methods in proteomic experiments. When
effectively used, proteomics may provide extensive information about proteins and their post …

Development of PEGylated cysteine-modified lysine dendrimers with multiple reduced thiols to prevent hepatic ischemia/reperfusion injury

H Katsumi, M Nishikawa, R Hirosaki… - Molecular …, 2016 - ACS Publications
To inhibit hepatic ischemia/reperfusion injury, we developed polyethylene glycol (PEG)
conjugated (PEGylated) cysteine-modified lysine dendrimers with multiple reduced thiols …

Mass spectrometry for the detection of potential psychiatric biomarkers

AG Ngounou Wetie, I Sokolowska… - Journal of Molecular …, 2013 - Springer
The search for molecules that can act as potential biomarkers is increasing in the scientific
community, including in the field of psychiatry. The field of proteomics is evolving and its …

Structural characterization and disulfide assignment of spider peptide Phα1β by mass spectrometry

KL Wormwood, AG Ngounou Wetie… - Journal of the …, 2018 - ACS Publications
Native Phα1β is a peptide purified from the venom of the armed spider Phoneutria
nigriventer that has been shown to have an extensive analgesic effect with fewer side effects …

Mass spectrometry for proteomics-based investigation

AG Woods, I Sokolowska, AG Ngounou Wetie… - Advancements of Mass …, 2019 - Springer
Within the past years, we have witnessed a great improvement is mass spectrometry (MS)
and proteomics approaches in terms of instrumentation, protein fractionation, and …