Emerging translational research in neurological and psychiatric diseases: From in vitro to in vivo models

M Tanaka, Á Szabó, L Vécsei… - International journal of …, 2023 - mdpi.com
Revealing the underlying pathomechanisms of neurological and psychiatric disorders,
searching for new biomarkers, and developing novel therapeutics all require translational …

Neural correlates and molecular mechanisms of memory and learning

S Battaglia, A Avenanti, L Vécsei, M Tanaka - International journal of …, 2024 - mdpi.com
Memory and learning are essential cognitive processes that enable us to obtain, retain, and
recall information. These factors are crucial for survival, adaptation, and creativity. However …

From lab to life: Exploring cutting-edge models for neurological and psychiatric disorders

M Tanaka, L Vécsei - Biomedicines, 2024 - mdpi.com
Neuroscience, neurology, and psychiatry are rapidly evolving fields that aim to understand
the complex mechanisms underlying brain function and dysfunction, as well as to develop …

The Impact of C-3 Side Chain Modifications on Kynurenic Acid: A Behavioral Analysis of Its Analogs in the Motor Domain

D Martos, B Lőrinczi, I Szatmári, L Vécsei… - International journal of …, 2024 - mdpi.com
The central nervous system (CNS) is the final frontier in drug delivery because of the blood–
brain barrier (BBB), which poses significant barriers to the access of most drugs to their …

[HTML][HTML] Advances and Challenges in Gene Therapy for Neurodegenerative Diseases: A Systematic Review

N García-González, J Gonçalves-Sánchez… - International Journal of …, 2024 - mdpi.com
This review explores recent advancements in gene therapy as a potential treatment for
neurodegenerative diseases, focusing on intervention mechanisms, administration routes …

[HTML][HTML] Functional characterization and therapeutic potential of human umbilical cord blood mononuclear cells

Y Zhang, Y Lu, X Hu, M Jiang, Z Chen, L Jin, M Li… - Regenerative …, 2025 - Elsevier
Human umbilical cord blood mononuclear cells (hUCB-MNCs) are a population of cells
derived from neonatal cord blood, encompassing various stem cells and immune cells. The …

[HTML][HTML] Biosafety Evaluation of a Chimeric Adenoviral Vector in Mini-Pigs: Insights into Immune Tolerance and Gene Therapy Potential

A Izmailov, I Minyazeva, V Markosyan, Z Safiullov… - Biomedicines, 2024 - mdpi.com
Background: The biosafety of gene therapy products remains a major challenge to their
introduction into the clinic. In particular, the problem of immunogenicity of viral vectors is the …

Terapia génica en enfermedades neurodegenerativas

N García González - 2024 - gredos.usal.es
[ES] Analizamos el uso de las terapias génicas como medio para desarrollar nuevos
tratamientos en las enfermedades neurodegenerativas, evaluando los niveles de …