The geographical distribution of scorpions, implication of venom toxins, envenomation, and potential therapeutics in Southern and Northern Africa

IG Mabunda, NK Zinyemba, S Pillay… - Toxicology …, 2024 - academic.oup.com
Scorpions are predatory arachnids whose venomous sting primarily affects people in
tropical and subtropical regions. Most scorpion stings can only cause localized pain without …

In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

ML Salem, NM Shoukry, WK Teleb, MM Abdel-Daim… - Springerplus, 2016 - Springer
Scorpion venom is a highly complex mixture of about 100–700 different components, where
peptides are the major constituents with various biological and pharmacological properties …

Venoms of Iranian scorpions (Arachnida, Scorpiones) and their potential for drug discovery

SM Kazemi, JM Sabatier - Molecules, 2019 - mdpi.com
Scorpions, a characteristic group of arthropods, are among the earliest diverging arachnids,
dating back almost 440 million years. One of the many interesting aspects of scorpions is …

Unique diversity of the venom peptides from the scorpion Androctonus bicolor revealed by transcriptomic and proteomic analysis

L Zhang, W Shi, XC Zeng, F Ge, M Yang, Y Nie… - Journal of …, 2015 - Elsevier
Androctonus bicolor is one of the most poisonous scorpion species in the world. However,
little has been known about the venom composition of the scorpion. To better understand the …

The first report on transcriptome analysis of the venom gland of Iranian scorpion, Hemiscorpius lepturus

F Kazemi-Lomedasht, V Khalaj, KP Bagheri… - Toxicon, 2017 - Elsevier
Hemiscorpius lepturus scorpion is one of the most venomous members of the
Hemiscorpiidae family. H. lepturus is distributed in Iran, Iraq and Yemen. The prevalence …

Mass-Spectrometry-Based Lipidome and Proteome Profiling of Hottentotta saulcyi (Scorpiones: Buthidae) Venom

P Ghezellou, K Jakob, J Atashi, A Ghassempour… - Toxins, 2022 - mdpi.com
Scorpion venom is a complex secretory mixture of components with potential biological and
physiological properties that attracted many researchers due to promising applications from …

Ethnomedicines for the treatment of scorpion stings: A perspective study

S Nath, AK Mukherjee - Journal of ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Scorpion sting is a public health concern with limited
clinical symptomatic treatment. The clinical treatment uses anti-scorpion antivenom and …

[HTML][HTML] Scorpion crude venom induced apoptosis and structural changes of Echinococcus granulosus protoscolices

ES Al-Malki, MM Aljedaie, OSO Amer… - Journal of King Saud …, 2022 - Elsevier
Echinococcus granulosus parasitic infection in humans causes hydatidosis (also known as
echinococcosis), which is a severe zoonotic illness that puts public health at risk. This …

Cytotoxic activity and mechanism of action of Smp43 scorpion peptide against colorectal cancer cell line HCT-116

MM Gerges, MA Abdel-Rahman, TR Rahmy… - Toxin …, 2024 - Taylor & Francis
This study was conducted to extend our previous investigations to examine the cytotoxic
efficacy of Smp43 scorpion peptide against colorectal cancer cell line (HCT-116) and …

Taking the sting out of scorpions: Electrophysiological investigation of the relative efficacy of three antivenoms against medically significant Centruroides species

SID Campbell, CY Chow, E Neri-Castro… - … and Physiology Part C …, 2024 - Elsevier
In this study, we report the innovative application of whole-cell patch-clamp
electrophysiology in assessing broad-spectrum neutralisation by three different antivenoms …