The concept of “type 3 diabetes” has emerged to define alterations in glucose metabolism
that predispose individuals to the development of Alzheimer's disease (AD). Novel evidence …

Adipose tissue was previously regarded as a dormant organ for lipid storage until the
identification of adiponectin and leptin in the early 1990s. This revelation unveiled the …

Exogenous insulin-like growth factor-1 (IGF-1) has been reported to promote wound healing
through regulation of vascular endothelial cells (VECs). Despite the existing studies of IGF-1 …

Low-load resistance training with blood flow restriction (LRT-BFR) has shown potential to
improve muscle strength and mass in different populations; however, there remains limited …

Hypopituitarism is a highly heterogeneous multisystem disorder that can have a major
impact on long-term morbidity and mortality, but even more so during acute medical …

Vascular smooth muscle cells (VSMCs) proliferation is a critical event that contributes to the
pathogenesis of vascular remodeling such as hypertension, restenosis, and pulmonary …

Insulin-like Growth Factor-1 (IGF-1) is a crucial mitogenic factor with important functions in
the mammary gland, mainly through its interaction with the IGF-1 receptor (IGF-1R). This …

Heart failure is a complex syndrome characterized by cardiac hypertrophy, fibrosis, and
diastolic/systolic dysfunction. These changes share many pathological features with …

Lung cancer is a prevalent and very aggressive sickness that will likely claim 1.8 million
lives by 2022, with an estimated 2.2 million additional cases expected worldwide. The goal …

Background Insulin-like growth factor 1 (IGF-1) plays a vital role in the attainment and
maintenance of bone mass throughout life and is closely related to the stature of children. 25 …