A synergistic therapy against influenza virus A/H1N1/PR8 by a HA1 specific neutralizing single-domain VL and an RNA hydrolyzing scFv

PT Hoang, QXT Luong, RQ Ayun, Y Lee… - Frontiers in …, 2024 - frontiersin.org
The emergence of anti-influenza drug-resistant strains poses a challenge for influenza
therapy due to mutations in the virus's surface protein. Recently, there has been increasing …

Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases

J Finney, M Kuraoka, S Song, A Watanabe, X Liang… - bioRxiv, 2025 - biorxiv.org
The discovery of broadly protective antibodies to the influenza virus neuraminidase (NA) has
raised interest in NA as a vaccine target. However, recombinant, solubilized tetrameric NA …