Innate immunity: the first line of defense against SARS-CoV-2

MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

[HTML][HTML] Long COVID and its Management

HC Koc, J Xiao, W Liu, Y Li, G Chen - International journal of …, 2022 - ncbi.nlm.nih.gov
The pandemic of COVID-19 is the biggest public health crisis in 21 st Century. Besides the
acute symptoms after infection, patients and society are also being challenged by the long …

Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections

P Zimmermann, N Curtis - Archives of disease in childhood, 2021 - adc.bmj.com
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …

A comprehensive review of the global efforts on COVID-19 vaccine development

Y Li, R Tenchov, J Smoot, C Liu, S Watkins… - ACS Central …, 2021 - ACS Publications
A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development | ACS
Central Science ACS ACS Publications C&EN CAS Find my institution Log In ACS Central …

[HTML][HTML] Assessing the burden of COVID-19 in developing countries: systematic review, meta-analysis and public policy implications

AT Levin, N Owusu-Boaitey, S Pugh, BK Fosdick… - BMJ Global …, 2022 - gh.bmj.com
Introduction The infection fatality rate (IFR) of COVID-19 has been carefully measured and
analysed in high-income countries, whereas there has been no systematic analysis of age …

Vaccines for COVID-19

JS Tregoning, ES Brown… - Clinical & …, 2020 - academic.oup.com
Since the emergence of COVID-19, caused by the SARS-CoV-2 virus at the end of 2019,
there has been an explosion of vaccine development. By 24 September 2020, a staggering …

Recent developments in the immunopathology of COVID‐19

H Zhang, Y Sun, Y Wang, D Yazici, D Azkur, I Ogulur… - Allergy, 2023 - Wiley Online Library
There has been an important change in the clinical characteristics and immune profile of
Coronavirus disease 2019 (COVID‐19) patients during the pandemic thanks to the …

BCG vaccination stimulates integrated organ immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance

A Lee, K Floyd, S Wu, Z Fang, TK Tan, HM Froggatt… - Nature …, 2024 - nature.com
Abstract Bacille Calmette–Guérin (BCG) vaccination can confer nonspecific protection
against heterologous pathogens. However, the underlying mechanisms remain mysterious …

[HTML][HTML] COVID-19 and the human innate immune system

JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …

100 years of Bacillus Calmette–Guérin immunotherapy: from cattle to COVID-19

N Lobo, NA Brooks, AR Zlotta, JD Cirillo… - Nature Reviews …, 2021 - nature.com
Abstract Bacillus Calmette–Guérin (BCG) is the most widely used vaccine worldwide and
has been used to prevent tuberculosis for a century. BCG also stimulates an anti-tumour …