Management of treatment-resistant depression: challenges and strategies

D Voineskos, ZJ Daskalakis… - … disease and treatment, 2020 - Taylor & Francis
Abstract Treatment-resistant depression (TRD) is a subset of Major Depressive Disorder
which does not respond to traditional and first-line therapeutic options. There are several …

Defining treatment‐resistant depression

BN Gaynes, L Lux, G Gartlehner, G Asher… - Depression and …, 2020 - Wiley Online Library
Background Varying conceptualizations of treatment‐resistant depression (TRD) have made
translating research findings or systematic reviews into clinical practice guidelines …

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial

DM Blumberger, F Vila-Rodriguez, KE Thorpe, K Feffer… - The Lancet, 2018 - thelancet.com
Background Treatment-resistant major depressive disorder is common; repetitive
transcranial magnetic stimulation (rTMS) by use of high-frequency (10 Hz) left-side …

Automated optimization of TMS coil placement for personalized functional network engagement

CJ Lynch, IG Elbau, TH Ng, D Wolk, S Zhu, A Ayaz… - Neuron, 2022 - cell.com
Transcranial magnetic stimulation (TMS) is used to treat multiple psychiatric and
neurological conditions by manipulating activity in particular brain networks and circuits, but …

Effectiveness of standard sequential bilateral repetitive transcranial magnetic stimulation vs bilateral theta burst stimulation in older adults with depression: the FOUR …

DM Blumberger, BH Mulsant, KE Thorpe… - JAMA …, 2022 - jamanetwork.com
Importance Treatment-resistant depression (TRD) is common in older adults. Bilateral
repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex for 48 …

Consensus recommendations for the clinical application of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression

SM McClintock, IM Reti, LL Carpenter… - The Journal of clinical …, 2017 - psychiatrist.com
Objective: To provide expert recommendations for the safe and effective application of
repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depressive …

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 4 …

RV Milev, P Giacobbe, SH Kennedy… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Cortico-striatal-thalamic loop circuits of the salience network: a central pathway in psychiatric disease and treatment

SK Peters, K Dunlop, J Downar - Frontiers in systems neuroscience, 2016 - frontiersin.org
The salience network (SN) plays a central role in cognitive control by integrating sensory
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …

[HTML][HTML] The identification, assessment and management of difficult-to-treat depression: an international consensus statement

RH McAllister-Williams, C Arango, P Blier… - Journal of Affective …, 2020 - Elsevier
Background Many depressed patients are not able to achieve or sustain symptom remission
despite serial treatment trials–often termed “treatment resistant depression”. A broader …

Major depressive disorder

C Otte, SM Gold, BW Penninx, CM Pariante… - Nature reviews Disease …, 2016 - nature.com
Major depressive disorder (MDD) is a debilitating disease that is characterized by
depressed mood, diminished interests, impaired cognitive function and vegetative …