The potential of traditional knowledge to develop effective medicines for the treatment of leishmaniasis

LFD Passero, ES Brunelli, T Sauini… - Frontiers in …, 2021 - frontiersin.org
Leishmaniasis is a neglected tropical disease that affects people living in tropical and
subtropical areas of the world. There are few therapeutic options for treating this infectious …

Preliminary phytochemical screening for antioxidant activity and content of phenols and flavonoids of 18 species of plants native to western Ecuador

S Moncayo, X Cornejo, J Castillo… - Trends in Phytochemical …, 2021 - tpr.shahrood.iau.ir
The phytochemical screening, total phenolics and flavonoids content and antioxidant activity
of plants native to western Ecuador were investigated to provide the basic information for …

Efficacy of lapachol on treatment of cutaneous and visceral leishmaniasis

IAC Araújo, RC de Paula, CL Alves, KF Faria… - Experimental …, 2019 - Elsevier
Leishmaniasis is one of the most important neglected diseases worldwide. It is a life-
threatening disease and causes significant morbidity, long-term disability, and early death …

DFT study and antiparasitic activity of some azo dyes containing uracil

N Süleymanoğlu, P Kubaşık, Ş Direkel - Journal of Chemistry, 2021 - Wiley Online Library
In this study, for the first time, molecular modeling and antiparasitic activity studies were
carried out on some azo dyes containing uracil, 6‐amino‐5‐[(4‐nitrophenyl) diazenyl] …

[HTML][HTML] In vitro antileishmanial activity and molecular docking studies of lupeol and monostearin, isolated from Parkia biglobosa

T Osafo, TJ Philips, AK Adomako, LS Borquaye… - Scientific African, 2023 - Elsevier
Parkia biglobosa (Leguminosae) is used traditionally for managing leishmaniasis. However,
there are no reports of the antileishmanial constituents from the plant. This study is aimed at …

Antituberculosis activities of lapachol and β-lapachone in combination with other drugs in Acidic pH

AL Ieque, HC Carvalho, VP Baldin… - Microbial Drug …, 2021 - liebertpub.com
Background: The treatment of multidrug-resistant tuberculosis (MDR-TB) is a challenge to be
overcome. The increase of resistant isolates associated with serious side effects during …

In Vitro Anti-Toxoplasma Activity of Extracts Obtained from Tabebuia rosea and Tabebuia chrysantha: The Role of β-Amyrin

MC Cardona-Trujillo, FJ Jiménez-González, LA Veloza… - Molecules, 2024 - mdpi.com
Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii that is
highly prevalent worldwide. Although the infection is asymptomatic in immunocompetent …

Influence of arbuscular mycorrhizal fungi density on growth and metabolism of Handroanthus serratifolius (Vahl) SO Grose seedlings

LS da Sousa, TS Correia, FDS Dos Farias… - Physiologia …, 2023 - Wiley Online Library
Studies on the relationship between Handroanthus serratifolius and arbuscular mycorrhizal
fungi (AMF) are limited in the literature. The influence of AMF spore density on plant …

[HTML][HTML] Selective in vitro antileishmanial activity of Mimosa caesalpiniifolia stem barks and its main constituent betulinic acid against Leishmania amazonensis

LM Brito, MM de Moraes Alves, AC Souza… - South African Journal of …, 2021 - Elsevier
Introduction The need of novel antileishmanial compounds with a wide therapeutic index
has been a challenge for the pharmaceutical industry in reducing the side effects resulted …

Antimicrobial activity of Mimosa caesalpiniifolia Benth and its interaction with antibiotics against Staphylococcus aureus strains overexpressing efflux pump genes

SWC Silva, NBN Monção, BQ Araújo… - Letters in applied …, 2019 - academic.oup.com
This study aimed to evaluate the antimicrobial activity of the dichloromethane fraction
(DCMF) from the stem bark of Mimosa caesalpiniifolia and its effect on the activity of …