Melanosome transport and regulation in development and disease

X Tian, Z Cui, S Liu, J Zhou, R Cui - Pharmacology & therapeutics, 2021 - Elsevier
Melanosomes are specialized membrane-bound organelles that synthesize and organize
melanin, ultimately providing color to the skin, hair, and eyes. Disorders in melanogenesis …

Rhododendrol‐induced leukoderma update II: Pathophysiology, mechanisms, risk evaluation, and possible mechanism‐based treatments in comparison with vitiligo

S Inoue, I Katayama, T Suzuki… - The Journal of …, 2021 - Wiley Online Library
A small proportion of individuals utilizing cosmetics containing rhododendrol developed
leukoderma with various pathological conditions, in some cases indistinguishable from …

Transcriptome and differential methylation integration analysis identified important differential methylation annotation genes and functional epigenetic modules related …

Y Pu, X Chen, Y Chen, L Zhang, J Chen… - Frontiers in …, 2021 - frontiersin.org
Vitiligo is an pigmentation disorder caused by a variety of pathogenic factors; its main
pathophysiological conditions include oxidative stress, immune activation, and genetic …

Isobutylamido thiazolyl resorcinol for prevention of UVB‐induced hyperpigmentation

V Vachiramon, C Kositkuljorn… - Journal of Cosmetic …, 2021 - Wiley Online Library
Background Isobutylamido thiazolyl resorcinol (ITR, Thiamidol®) has been proposed as a
potent tyrosinase inhibitor. A formulation containing ITR has recently shown promising …

Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia …

CH Yu, SQ Yang, L Li, Y Xin, F Zhang, XF Liu… - BMC Pharmacology and …, 2022 - Springer
Background Hydroquinone (HQ) is a phenolic metabolite of benzene with a potential risk for
hematological disorders and hematotoxicity in humans. In the present study, an integrative …

[HTML][HTML] Xiaoyin Jiedu Granules may alleviate psoriasis-like skin diseases in mice by regulating sphingosine 1-phosphate receptor expression and reducing Th17 …

Z Wang, G Zhang, H Zhang, L Li - Heliyon, 2023 - cell.com
Abstract Sphingosine-1-phosphate (S1P) is associated with the onset and severity of
psoriasis, a chronic inflammatory skin disease linked to innate and adaptive immune …

Establishment and validation of evaluation models for post-inflammatory pigmentation abnormalities

Y Zhang, H Zeng, Y Hu, L Jiang, C Fu, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Post-inflammatory skin hyper-or hypo-pigmentation is a common occurrence with unclear
etiology. There is currently no reliable method to predict skin pigmentation outcomes after …

Based on network pharmacology and bioinformatics to analyze the mechanism of action of Astragalus membranaceus in the treatment of vitiligo and COVID-19

Y Wang, M Ding, J Chi, T Wang, Y Zhang, Z Li, Q Li - Scientific Reports, 2023 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is spreading rapidly around the world.
However, the treatment of vitiligo combined with COVID-19 has not been reported …

Feasibility of oral tranexamic acid for vitiligo patients with melasma

PH Chiang, YJ Lin, YC Chiu, WH Chung… - Dermatologic …, 2021 - Wiley Online Library
Melasma and vitiligo are both common pigmentary disorders, and the treatment is
challenging. Oral tranexamic acid (TA) is effective for refractory melasma; however, the …

Key hepatic signatures of human and mouse nonalcoholic steatohepatitis: A transcriptome–proteome data meta-analysis

JJ Pyo, Y Choi - Frontiers in Endocrinology, 2022 - frontiersin.org
Background Despite the global prevalence of nonalcoholic fatty liver disease (NAFLD), its
pathophysiology remains unclear. In this study, we established highly confident …