Natural products: An upcoming therapeutic approach to cancer

S Dutta, S Mahalanobish, S Saha, S Ghosh… - Food and Chemical …, 2019 - Elsevier
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

Biological activities of gedunin—A limonoid from the Meliaceae family

TM Braga, L Rocha, TY Chung, RF Oliveira, C Pinho… - Molecules, 2020 - mdpi.com
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly
in seeds. Several biological activities have been attributed to gedunin, including …

Atranorin, an antimicrobial metabolite from lichen Parmotrema rampoddense exhibited in vitro anti-breast cancer activity through interaction with Akt activity

A Harikrishnan, V Veena, B Lakshmi… - Journal of …, 2021 - Taylor & Francis
Atranorin (ATR), lichenized secondary metabolite and depside molecule with several
biological potentials such as antimicrobial, anticancer, anti-inflammatory, antinociceptive …

In vitro anticancer effect of gedunin on human teratocarcinomal (NTERA‐2) cancer stem‐like cells

L Tharmarajah, SR Samarakoon… - BioMed research …, 2017 - Wiley Online Library
Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the
present study, antiproliferative potential of gedunin was evaluated in human embryonal …

In silico identification and in vitro validation of alpha-hederin as a potent inhibitor of Wnt/β-catenin signaling pathway in breast cancer stem cells

TP Saliu, NN Seneviratne, M Faizan… - In Silico …, 2024 - Springer
Cancer stem cells (CSCs) play a vital role in metastasis, recurrence and chemoresistance in
breast cancer. β-catenin, which is a frequently over activated protein in CSCs, binds to T-cell …

Computational modelling and docking insight of bacterial peptide as ideal anti-tubercular and anticancer agents

A Khusro, C Aarti, P Agastian - Biocatalysis and Agricultural Biotechnology, 2020 - Elsevier
The present investigation was assessed to predict the anti-tubercular and anticancer
attributes of bacterial peptide SMANF2 using in silico docking tool. Initially, the structure of …

Pharmaceutical Potential of Constituents from Azadirachta indica and their Specific Role as Anti-cancer Agents

I Jeelani, M Bhosale, T Qadir, PK Sharma… - Current Bioactive …, 2023 - benthamdirect.com
Neem (Azadirachta indica), a Meliaceae family member, is a rapidly growing tropical
evergreen tree with a thick, branching trunk. It has been used for hundreds of years in …

Cytotoxic and xanthine oxidase inhibitory activities of chemical constituents of Alphonsea Cylindrica King

YM Bakri, AKO Aldulaimi, SSSA Azziz… - Research Journal of …, 2019 - indianjournals.com
This study aimed to investigate the chemical constituents from Alphonsea cylindrica as well
as their cytotoxic and xanthine oxidase inhibitory activities. The chemical compounds were …

[PDF][PDF] Research Article In Vitro Anticancer Effect of Gedunin on Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells

L Tharmarajah, SR Samarakoon, MK Ediriweera… - 2017 - academia.edu
Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the
present study, antiproliferative potential of gedunin was evaluated in human embryonal …