Short-chain fatty acids in chronic kidney disease: Focus on inflammation and oxidative stress regulation

G Magliocca, P Mone, BR Di Iorio, A Heidland… - International Journal of …, 2022 - mdpi.com
Chronic Kidney Disease (CKD) is a debilitating disease associated with several secondary
complications that increase comorbidity and mortality. In patients with CKD, there is a …

The role of short-chain fatty acids of gut microbiota origin in hypertension

Y Wu, H Xu, X Tu, Z Gao - Frontiers in Microbiology, 2021 - frontiersin.org
Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases,
and its development involves multiple mechanisms. Gut microbiota has been reported to be …

Vegetable-based diets for chronic kidney disease? It is time to reconsider

A Cases, S Cigarrán-Guldrís, S Mas, E Gonzalez-Parra - Nutrients, 2019 - mdpi.com
Traditional dietary recommendations to renal patients limited the intake of fruits and
vegetables because of their high potassium content. However, this paradigm is rapidly …

Lipid metabolite biomarkers in cardiovascular disease: Discovery and biomechanism translation from human studies

P McGranaghan, JA Kirwan, MA Garcia-Rivera… - Metabolites, 2021 - mdpi.com
Lipids represent a valuable target for metabolomic studies since altered lipid metabolism is
known to drive the pathological changes in cardiovascular disease (CVD). Metabolomic …

[HTML][HTML] The microbiome and host mucosal interactions in urinary tract diseases

B Jones-Freeman, M Chonwerawong, VR Marcelino… - Mucosal …, 2021 - Elsevier
The urinary tract consists of the bladder, ureters, and kidneys, and is an essential organ
system for filtration and excretion of waste products and maintaining systemic homeostasis …

Inflammation and gut dysbiosis as drivers of CKD–MBD

P Evenepoel, P Stenvinkel, C Shanahan… - Nature Reviews …, 2023 - nature.com
Abstract Two decades ago, Kidney Disease: Improving Global Outcomes coined the term
chronic kidney disease–mineral and bone disorder (CKD–MBD) to describe the syndrome of …

Chronic kidney disease, gut dysbiosis, and constipation: a burdensome triplet

R Ikee, N Sasaki, T Yasuda, S Fukazawa - Microorganisms, 2020 - mdpi.com
Gut dysbiosis has been implicated in the progression of chronic kidney disease (CKD).
Alterations in the gut environment induced by uremic toxins, the dietary restriction of fiber …

Cardiovascular risk of metabolically healthy obesity in two european populations: Prevention potential from a metabolomic study

D Wei, V González-Marrachelli, JD Melgarejo… - Cardiovascular …, 2023 - Springer
Background A new definition of metabolically healthy obesity (MHO) has recently been
proposed to stratify the heterogeneous mortality risk of obesity. Metabolomic profiling …

[HTML][HTML] Empagliflozin ameliorates atherosclerosis via regulating the intestinal flora

H Hao, Z Li, S Qiao, Y Qi, X Xu, J Si, Y Liu, L Chang… - Atherosclerosis, 2023 - Elsevier
Background and aims Sodium-glucose cotransporter 2 inhibitor (SGLT2i) has been reported
to attenuate atherosclerosis. Further, it has been suggested that intestinal flora influences …

The change of gut microbiota‐derived short‐chain fatty acids in diabetic kidney disease

C Zhong, Z Dai, L Chai, L Wu, J Li… - Journal of Clinical …, 2021 - Wiley Online Library
Background Previous studies found the dysbiosis of intestinal microbiota in diabetic kidney
disease (DKD), especially the decreased SCFA‐producing bacteria. We aimed to …